This second section of our medication database entry focuses on potential side effects, withdrawal or discontinuation effects, and additional information, while part one covers basic drug characteristics, uses and benefits.
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What are the possible side effects of primidone?
- If you experience any of the following serious side effects, stop taking primidone and seek emergency medical attention:
- an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
- a rash;
- worsening of seizures; or
- a fever.
- Other, less serious side effects may be more likely to occur. Continue to take primidone and talk to your doctor if you experience
- dizziness, poor coordination, or drowsiness;
- blurred or double vision;
- irregular back-and-forth movements of the eyes; or
- nausea and vomiting.
- Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
What other drugs will affect primidone?
- Primidone interacts with most other antiepileptic medicines.
- Acetazolamide (Diamox), carbamazepine (Tegretol), ethosuximide (Zarontin), and methsuximide (Celontin) may all decrease the effects of primidone, and larger primidone doses may be necessary.
- Phenytoin (Dilantin), ethotoin (Peganone), mephenytoin (Mesantoin), and isoniazid (Nydrazid) may increase blood levels of primidone. An adjustment of your primidone dosage may be necessary.
- Carbamazepine (Tegretol) blood levels may be higher during therapy with primidone. An adjustment of the carbamazepine dosage may be necessary.
- Drugs other than those listed here may also interact with primidone. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.
Where can I get more information?
- Your pharmacist has additional information about primidone written for health professionals that you may read.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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Although we have made considerable efforts to ensure that the information provided here is accurate, up-to-date, and complete, MedLibrary.org makes no guarantee to that effect. Drug information contained herein may be time sensitive. This medication information does not endorse drugs, diagnose patients or recommend any specific pharmacotherapy. This is an educational resource only -- intended to supplement but not to replace the expertise, skill, knowledge and judgment of medically qualified healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, please check with your doctor, nurse or local pharmacist. MedLibrary.org does not assume any responsibility for any aspect of healthcare administered with the aid of information provided here.
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Version: 2.04. Revision Date: 2/14/03.