Part Two of Augmentin Information, Focusing on Side Effects, Discontinuation or Withdrawal Effects, and Additional Information

This second section of our medication database entry focuses on potential side effects, withdrawal or discontinuation effects, and additional information, while part one covers basic drug characteristics, uses and benefits.

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What are the possible side effects of amoxicillin and clavulanate potassium?

  • If you experience any of the following serious side effects, stop taking amoxicillin and clavulanate potassium and seek emergency medical attention or contact your doctor immediately:
    • an allergic reaction (shortness of breath; closing of the throat; hives; swelling of the lips, face, or tongue; rash; or fainting); or
    • diarrhea that is severe or lasts longer than 3 days.
  • Other, less serious side effects may be more likely to occur. Continue to take amoxicillin and clavulanate potassium and talk to your doctor if you experience
    • mild diarrhea;
    • nausea or vomiting;
    • rash;
    • white patches in the mouth (thrush/yeast infection); or
    • vaginal yeast infection or diaper rash.
  • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect amoxicillin and clavulanate potassium?

  • Before taking amoxicillin and clavulanate potassium, tell your doctor if you are taking any of the following drugs:
    • allopurinol (Zyloprim);
    • probenecid (Benemid); or
    • another antibiotic (for the same or for a different infection).
  • You may not be able to take amoxicillin and clavulanate potassium, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.
  • Amoxicillin and clavulanate potassium may decrease the effectiveness of birth control pills. Use a second method of birth control while taking amoxicillin and clavulanate potassium to ensure protection from unintended pregnancy.
  • Drugs other than those listed here may also interact with amoxicillin and clavulanate potassium. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Where can I get more information?

  • Your pharmacist has additional information about amoxicillin and clavulanate potassium written for health professionals that you may read.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Limitations and the Source of Our Online Medication Information Database

Although we have made considerable efforts to ensure that the information provided here is accurate, up-to-date, and complete, MedLibrary.org makes no guarantee to that effect. Drug information contained herein may be time sensitive. This medication information does not endorse drugs, diagnose patients or recommend any specific pharmacotherapy. This is an educational resource only -- intended to supplement but not to replace the expertise, skill, knowledge and judgment of medically qualified healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, please check with your doctor, nurse or local pharmacist. MedLibrary.org does not assume any responsibility for any aspect of healthcare administered with the aid of information provided here.

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Version: 5.01. Revision date: 8/12/03.

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