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What are the possible side effects of buspirone?

• If you experience any of the following serious side effects, stop taking buspirone and seek emergency medical attention:
• an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; hives);
• chest pain or an irregular heartbeat;
• headache, dizziness, lightheadedness, slurred speech, confusion, or blurred vision;
• numbness or tingling in your hands, feet, arms, or legs;
• depression; or
• uncontrollable movements of your arms, legs, tongue, or lips.
• Other, less serious side effects may be more likely to occur. Continue to take buspirone and talk to your doctor if you experience
• drowsiness or fatigue,
• dry mouth, or
• an increase in nightmares or dreams.
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect buspirone?

• Do not take buspirone if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) during the last 2 weeks. Severely high blood pressure may occur if buspirone is taken with a monoamine oxidase inhibitor.
• Before taking buspirone, tell your doctor if you are taking any of the following medicines:
• nefazodone (Serzone);
• itraconazole (Sporanox);
• erythromycin (E-Mycin, E.E.S., Ery-Tab, Eryc, others); or
• selegiline (Eldepryl).
• You may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.
• Buspirone may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, and muscle relaxants. Tell your doctor about all medicines that you are taking, and do not take any prescription or over-the-counter medicine without first talking to your doctor.
• Drugs other than those listed here may also interact with buspirone. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Where can I get more information?

• Your pharmacist has additional information about buspirone written for health professionals that you may read.
• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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Although we have made considerable efforts to ensure that the information provided here is accurate, up-to-date, and complete, MedLibrary.org makes no guarantee to that effect. Drug information contained herein may be time sensitive. This medication information does not endorse drugs, diagnose patients or recommend any specific pharmacotherapy. This is an educational resource only -- intended to supplement but not to replace the expertise, skill, knowledge and judgment of medically qualified healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, please check with your doctor, nurse or local pharmacist. MedLibrary.org does not assume any responsibility for any aspect of healthcare administered with the aid of information provided here.

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Version: 3.05. Revision Date: 2/14/03.