Part Two of Lopid Information, Focusing on Side Effects, Discontinuation or Withdrawal Effects, and Additional Information

This second section of our medication database entry focuses on potential side effects, withdrawal or discontinuation effects, and additional information, while part one covers basic drug characteristics, uses and benefits.

What are the possible side effects of gemfibrozil?

  • If you experience any of the following serious side effects, stop taking gemfibrozil and seek emergency medical attention or contact your doctor immediately:
    • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
    • chest pain, shortness of breath, or an irregular heartbeat;
    • nausea, vomiting, stomach pain, or clay-colored stools;
    • yellowing of the skin or eyes (jaundice);
    • rash or itching;
    • sores in the mouth or on your lips;
    • swollen legs or feet;
    • chills, fever, or blood in the urine; or
    • muscle aches, pain, or cramping.
  • Other, less serious side effects may be more likely to occur. Continue to take gemfibrozil and talk to your doctor if you experience
    • indigestion;
    • headache, dizziness, or drowsiness; or
    • decreased sex drive.
  • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect gemfibrozil?

  • Gemfibrozil may increase the effects of the following drugs, which could lead to dangerous side effects:
    • an anticoagulants (blood thinner) such as warfarin (Coumadin);
    • insulin or an oral diabetes medication such as chlorpropamide (Diabenese), glipizide (Glucotrol), glyburide (Micronase, DiaBeta, Glynase), tolbutamide (Orinase), tolazamide (Tolinase), and acetohexamide (Dymelor), and others; or
    • another cholesterol-lowering drug such as atorvastatin (Lipitor), lovastatin (Mevacor, Altocor), simvastatin (Zocor), pravastatin (Pravachol), fluvastatin (Lescol, Lescol XL) .
  • You may not be able to take gemfibrozil, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the drugs listed above.
  • Drugs other than those listed here may also interact with gemfibrozil. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Where can I get more information?

  • Your pharmacist has additional information about gemfibrozil written for health professionals that you may read.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Limitations and the Source of Our Online Medication Information Database

Although we have made considerable efforts to ensure that the information provided here is accurate, up-to-date, and complete, MedLibrary.org makes no guarantee to that effect. Drug information contained herein may be time sensitive. This medication information does not endorse drugs, diagnose patients or recommend any specific pharmacotherapy. This is an educational resource only -- intended to supplement but not to replace the expertise, skill, knowledge and judgment of medically qualified healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, please check with your doctor, nurse or local pharmacist. MedLibrary.org does not assume any responsibility for any aspect of healthcare administered with the aid of information provided here.

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Version: 4.01. Revision date: 7/31/03.