Welcome to our glyburide information (part 2) -- just click to return to front page.

Or click here for clinical trials research information on glyburide.

What are the possible side effects of glyburide?

• Stop taking glyburide and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives).
• Other, less serious side effects from glyburide result mostly from blood sugar levels that are either too high or too low. You should be familiar with the symptoms of both high and low blood sugar levels and know how to treat both conditions. Also, be sure your family and close friends know how to help you in an emergency situation.
• Low blood sugar may occur when too much glyburide is taken; when meals are missed or delayed; if you exercise more than usual; during illness, especially with vomiting or diarrhea; if you take other medications; after drinking alcohol; and in other situations.
• Hypoglycemia or Low blood sugar has the following symptoms:
• shaking;
• headache;
• cold sweats;
• pale, cool skin;
• anxiety; and
• difficulty concentrating.
• Keep hard, sugary candy; chocolate; fruit juice; or glucose tablets on hand to treat episodes of low blood sugar.
• Increased blood sugar may occur when not enough glyburide is taken; if you eat significantly more food then usual; if you exercise less than usual; if you take other medications; during fever or other illness; and in other situations.
• Hyperglycemia or High blood sugar has the following symptoms:
• increased thirst,
• increased hunger, and
• increased urination.
• There may be an increased risk of death due to cardiovascular (heart and blood vessels) complications with the use of glyburide when compared to the treatment of diabetes with diet or diet plus insulin. The long-term use of glyburide should be discussed with your doctor.
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect glyburide?

• Many other medicines may increase or decrease the effects of glyburide or affect your condition. Before taking glyburide, tell your doctor if you are taking any of the following medicines:
• aspirin or another salicylate such as magnesium/choline salicylate (Trilisate), salsalate (Disalcid, others), choline salicylate (Arthropan), magnesium salicylate (Magan), or bismuth subsalicylate (Pepto-Bismol);
• a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin, Advil, Nuprin, others), ketoprofen (Orudis, Orudis KT, Oruvail), diclofenac (Voltaren, Cataflam), etodolac (Lodine), indomethacin (Indocin), nabumetone (Relafen), oxaprozin (Daypro), naproxen (Anaprox, Naprosyn, Aleve), and others;
• a sulfa-based drug such as sulfamethoxazole-trimethoprim (Bactrim, Septra), sulfisoxazole (Gantrisin), or sulfasalazine (Azulfidine);
• a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil);
• a beta-blocker such as propranolol (Inderal), atenolol (Tenormin), acebutolol (Sectral), metoprolol (Lopressor), and others;
• a diuretic (water pill) such as hydrochlorothiazide (HCTZ, Hydrodiuril), chlorothiazide (Diuril), and others;
• a steroid medicine such as prednisone (Deltasone, Orasone, others), methylprednisolone (Medrol, others), prednisolone (Prelone, Pediapred, others), and others;
• a phenothiazine such as chlorpromazine (Thorazine), fluphenazine (Prolixin, Permitil), prochlorperazine (Compazine), promethazine (Phenergan), and others;
• phenytoin (Dilantin);
• isoniazid (Nydrazid); or
• prescription, over-the-counter, or herbal cough, cold, allergy, or weight loss medications.
• You may require a dosage adjustment or special monitoring if you are taking any of the medicines listed above.
• Drugs other than those listed here may also interact with glyburide or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Where can I get more information?

• Your pharmacist has additional information about glyburide written for health professionals that you may read.
• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Limitations and the Source of Our Online Medication Information Database

Although we have made considerable efforts to ensure that the information provided here is accurate, up-to-date, and complete, MedLibrary.org makes no guarantee to that effect. Drug information contained herein may be time sensitive. This medication information does not endorse drugs, diagnose patients or recommend any specific pharmacotherapy. This is an educational resource only -- intended to supplement but not to replace the expertise, skill, knowledge and judgment of medically qualified healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, please check with your doctor, nurse or local pharmacist. MedLibrary.org does not assume any responsibility for any aspect of healthcare administered with the aid of information provided here.

Full public license and copyright information is available separately from Cerner Multum, Inc.

Version: 3.03. Revision date: 7/31/03.