Part Two of Precose Information, Focusing on Side Effects, Discontinuation or Withdrawal Effects, and Additional Information

This second section of our medication database entry focuses on potential side effects, withdrawal or discontinuation effects, and additional information, while part one covers basic drug characteristics, uses and benefits.

What are the possible side effects of acarbose?

  • Stop taking acarbose and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives).
  • No other serious side effects have been reported from the use of acarbose. Consult your doctor if you experience any unusual or especially bothersome side effects.
  • Know the signs and symptoms of hypoglycemia (low blood sugar), which include shaking; headache; sweating; pale, cool skin; fast heartbeats; drowsiness; dizziness; weakness; hunger; confusion; nausea; nervousness or anxiety; or difficulty concentrating. Carry a piece of non-dietetic, sugary hard candy or glucose tablets with you to treat episodes of low blood sugar.
  • Some gas, bloating, abdominal discomfort or pain is likely to be experienced. Diarrhea may also occur. These side effects usually lessen with time.
  • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect acarbose?

  • Digestive-enzyme supplements such as pancreatin (amylase, protease, lipase) in products such as Arco-Lase, Cotazym, Donnazyme, Pancrease, Creon, Ku-Zyme, and others may decrease the effects of acarbose. These medications should not be taken at the same time as acarbose.
  • Before taking acarbose, tell your doctor if you are taking any of the following medicines:
    • a thiazide diuretic (water pill) such as hydrochlorothiazide (HCTZ, Hydrodiuril, others), chlorothiazide (Diuril), chlorthalidone (Thalitone), indapamide (Lozol), and others;
    • a steroid medication such as prednisone (Deltasone), methylprednisolone (Medrol), and others;
    • an estrogen (Premarin, Ogen, others) or an estrogen-containing birth control pill;
    • a phenothiazine such as chlorpromazine (Thorazine), prochlorperazine (Compazine), promethazine (Phenergan, Promethegan), and others;
    • a thyroid medication (Synthroid, Levoxyl, others);
    • phenytoin (Dilantin, Phenytek); or
    • a calcium channel blocker such as verapamil (Calan, Verelan, Isoptin), diltiazem (Cardizem, Dilacor XR), nifedipine (Procardia, Adalat), and others.
  • The drugs listed above do not necessarily affect the actions of acarbose directly, but they are known to affect blood sugar levels. Special monitoring may be necessary.
  • Drugs other than those listed here may also interact with acarbose or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.

Where can I get more information?

  • Your pharmacist has more information about acarbose written for health professionals that you may read.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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Although we have made considerable efforts to ensure that the information provided here is accurate, up-to-date, and complete, MedLibrary.org makes no guarantee to that effect. Drug information contained herein may be time sensitive. This medication information does not endorse drugs, diagnose patients or recommend any specific pharmacotherapy. This is an educational resource only -- intended to supplement but not to replace the expertise, skill, knowledge and judgment of medically qualified healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, please check with your doctor, nurse or local pharmacist. MedLibrary.org does not assume any responsibility for any aspect of healthcare administered with the aid of information provided here.

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Version: 4.02. Revision date: 3/14/03.