Information on Reductil and How to Use It, Precautions and Other Medications to Avoid While Taking

This first section of our medication database entry focuses on basic drug characteristics, uses and benefits, while part two covers side effects, interactions and additional information.

Go to page: 1 | 2

Sibutramine (Reductil) Consumer Information

SIBUTRAMINE

Generic Name: sibutramine (oral) (sih BYOO tra meen)

Brand Names: Meridia

What is the most important information I should know about sibutramine?

  • Sibutramine has been reported to cause increased blood pressure in some patients. It is important to have your blood pressure and pulse monitored regularly while taking sibutramine.
  • Use caution when driving, operating machinery, or performing other hazardous activities. Sibutramine may cause dizziness, difficulty concentrating, or restlessness. If you experience these effects, avoid hazardous activities.
  • Do not take any other prescription or over-the-counter medicines without first talking to your doctor, especially weight-loss products, tryptophan (L-tryptophan, 5-HTP), decongestants, antidepressants, cough suppressants, lithium (Eskalith, Lithobid, Lithonate, others), and migraine medicines.

What is sibutramine?

  • Sibutramine affects chemicals in the body that are related to weight maintenance.
  • Sibutramine is used as a short-term supplement to diet and exercise in the treatment of obesity.
  • Sibutramine may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before taking sibutramine?

  • Do not take sibutramine without first talking to your doctor if you
    • have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil) in the last 14 days;
    • have anorexia nervosa;
    • are taking an appetite suppressant;
    • have high blood pressure;
    • have heart disease, irregular heartbeats, congestive heart failure, or a history of stroke;
    • have epilepsy or another seizure disorder;
    • have gallstones;
    • have glaucoma;
    • have liver disease; or
    • have kidney disease.
  • You may not be able to take sibutramine, or you may require a dosage adjustment or special monitoring if you have any of the conditions listed above.
  • Sibutramine is in the FDA pregnancy category C. This means that it is not known whether sibutramine will harm an unborn baby. Do not take sibutramine without first talking to your doctor if you are pregnant or could become pregnant during treatment.
  • It is not known whether sibutramine passes into breast milk. Do not take sibutramine without first talking to your doctor if you are breast-feeding a baby.
  • The safety and effectiveness of sibutramine have not been studied in children younger than 16 years of age.

How should I take sibutramine?

  • Take sibutramine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
  • Take each dose with a full glass of water.
  • Sibutramine is usually taken once a day. Follow your doctor's instructions.
  • Sibutramine can be taken with or without food.
  • Never take more of this medication than is prescribed for you. Too much sibutramine could be dangerous.
  • Sibutramine has been reported to cause increased blood pressure in some patients. It is important to have your blood pressure and pulse monitored regularly while taking sibutramine.
  • Store sibutramine at room temperature away from moisture and heat.

What happens if I miss a dose?

  • Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

  • Seek emergency medical attention.
  • Symptoms of a sibutramine overdose are not known.

What should I avoid while taking sibutramine?

  • Use caution when driving, operating machinery, or performing other hazardous activities. Sibutramine may cause dizziness, difficulty concentrating, or restlessness. If you experience these effects, avoid hazardous activities.
  • Do not take any other prescription or over-the-counter medicines without first talking to your doctor, especially weight-loss products, tryptophan (L-tryptophan, 5-HTP), decongestants, antidepressants, cough suppressants, lithium (Eskalith, Lithobid, Lithonate, others), and migraine medicines.

Go to page: 1 | 2

Please see the end of this document for relevant limitations, full details of our medication information supplier, and revision date or version number.