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What are the possible side effects of dicyclomine?

• If you experience any of the following serious side effects, stop taking dicyclomine and seek emergency medical attention:
• an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives); or
• an irregular or fast heart rate.
• Other, less serious side effects may be more likely to occur. Continue to take dicyclomine and talk to your doctor if you experience
• headache, dizziness, or lightheadedness;
• weakness or nervousness;
• blurred vision, large pupils;
• rash or itching;
• difficulty urinating;
• decreased sweating; or
• nasal congestion, stuffiness, or a dry mouth.
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect dicyclomine?

• Many other drugs may increase the side effects of dicyclomine. Before taking this medication, tell your doctor if you are taking any of the following medicines:
• amantadine (Symmetrel);
• quinidine (Quinaglute, Cardioquin, Quinora, Quinidex);
• antihistamines such as diphenhydramine (Benadryl, many others), brompheniramine (Dimetapp, Bromfed, many others), triprolidine (Actifed, others), and chlorpheniramine (Chlor-Trimeton, others), which are found in many over-the-counter and prescription cough, cold, and allergy medications;
• decongestants and appetite suppressants such as phenylpropanolamine (Dexatrim, others), phenylephrine (Neo-Synephrine, others), and pseudoephedrine (Sudafed, others), which are also found in many over-the-counter and prescription products;
• phenothiazines such as chlorpromazine (Thorazine) and prochlorperazine (Compazine);
• other commonly used phenothiazines, including fluphenazine (Prolixin), mesoridazine (Serentil), perphenazine (Trilafon), thioridazine (Mellaril), trifluoperazine (Stelazine), and promazine (Sparine);
• benzodiazepines (sleep and anxiety medications) such as alprazolam (Xanax) and diazepam (Valium);
• other commonly used benzodiazepines, including chlordiazepoxide (Librium), clorazepate (Tranxene), clonazepam (Klonopin), estazolam (Prosom), flurazepam (Dalmane), halazepam (Paxipam), lorazepam (Ativan), oxazepam (Serax), prazepam (Centrax), quazepam (Doral), temazepam (Restoril), and triazolam (Halcion);
• monoamine oxidase inhibitors (MAOIs) such as isocarboxazid (Marplan), tranylcypromine (Parnate), and phenelzine (Nardil);
• narcotic analgesics such as codeine (Tylenol #3, and many other prescription pain relievers), morphine (MS Contin, Roxanol, Astramorph, Duramorph), hydrocodone (Vicodin), and propoxyphene (Darvocet, Darvon, Wygesic);
• nitrates such as isosorbide dinitrate (Isordil, Sorbitrate) and isosorbide mononitrate (Imdur, ISMO);
• tricyclic antidepressants such as amitriptyline (Elavil, Endep), doxepin (Sinequan), and nortriptyline (Pamelor); or
• other commonly used tricyclic antidepressants, including: amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), imipramine (Tofranil), protriptyline (Vivactil), and trimipramine (Surmontil).
• Dicyclomine may increase the level of digoxin (Lanoxin, Lanoxicaps) in your blood. Tell your doctor if you are taking digoxin so that your digoxin levels can be monitored and changes in your dosage can be made if necessary.
• Do not take antacids at the same time as dicyclomine. They may decrease its absorption.
• Drugs other than those listed here may also interact with dicyclomine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Where can I get more information?

• Your pharmacist has more information about dicyclomine written for health professionals that you may read.
• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Limitations and the Source of Our Online Medication Information Database

Although we have made considerable efforts to ensure that the information provided here is accurate, up-to-date, and complete, MedLibrary.org makes no guarantee to that effect. Drug information contained herein may be time sensitive. This medication information does not endorse drugs, diagnose patients or recommend any specific pharmacotherapy. This is an educational resource only -- intended to supplement but not to replace the expertise, skill, knowledge and judgment of medically qualified healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, please check with your doctor, nurse or local pharmacist. MedLibrary.org does not assume any responsibility for any aspect of healthcare administered with the aid of information provided here.

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Version: 3.02. Revision Date: 2/14/03.