This second section of our medication database entry focuses on potential side effects, withdrawal or discontinuation effects, and additional information, while part one covers basic drug characteristics, uses and benefits.
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What are the possible side effects of atropine and diphenoxylate?
- If you experience any of the following serious side effects, stop taking atropine and diphenoxylate and seek emergency medical attention or call your doctor immediately:
- an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
- an irregular or fast heart rate;
- fever; or
- continuing diarrhea, abdominal pain, or abdominal distention.
- Other, less serious side effects may be more likely to occur. Continue to take atropine and diphenoxylate and talk to your doctor if you experience
- headache, dizziness, or lightheadedness;
- drowsiness;
- weakness or nervousness;
- blurred vision, dry eyes, large pupils, or sensitivity of the eyes to bright light;
- nausea, bloating, heartburn, or constipation;
- changes in taste;
- difficulty urinating;
- rash or flushing;
- decreased sweating; or
- nasal congestion, stuffiness, or a dry mouth.
- Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
What other drugs will affect atropine and diphenoxylate?
- Before taking this medication, tell your doctor if you have taken a monoamine oxidase inhibitor (MAOI) such as tranylcypromine (Parnate), isocarboxazid (Marplan), or phenelzine (Nardil) in the last 14 days. You may not be able to take atropine and diphenoxylate, or you may require special monitoring during your treatment.
- Atropine and diphenoxylate may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, and muscle relaxants. Tell your doctor about all medicines that you are taking, and do not take any medicine unless your doctor approves.
- Drugs other than those listed here may also interact with atropine and diphenoxylate. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.
Where can I get more information?
- Your pharmacist has more information about atropine and diphenoxylate written for health professionals that you may read.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Limitations and the Source of Our Online Medication Information Database
Although we have made considerable efforts to ensure that the information provided here is accurate, up-to-date, and complete, MedLibrary.org makes no guarantee to that effect. Drug information contained herein may be time sensitive. This medication information does not endorse drugs, diagnose patients or recommend any specific pharmacotherapy. This is an educational resource only -- intended to supplement but not to replace the expertise, skill, knowledge and judgment of medically qualified healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, please check with your doctor, nurse or local pharmacist. MedLibrary.org does not assume any responsibility for any aspect of healthcare administered with the aid of information provided here.
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Version: 1.04. Revision Date: 2/14/03.