This first section of our medication database entry focuses on basic drug characteristics, uses and benefits, while part two covers side effects, interactions and additional information.
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Reglan Consumer Information
REGLAN
Generic Name: metoclopramide (meh toe KLOE pra mide)
Brand Names: Reglan
What is the most important information I should know about metoclopramide?
- Call your doctor immediately if you experience uncontrollable movements or muscle spasms of your arms, legs, lips, jaw, tongue, face, or other body part; or if you experience unexplained anxiety, agitation, jitteriness, shortness of breath, or insomnia. These symptoms could be early signs of a serious side effect requiring immediate treatment.
- Use caution when driving, operating machinery, or performing other hazardous activities. Metoclopramide may cause drowsiness. If you experience drowsiness, avoid these activities.
What is metoclopramide?
- Metoclopramide increases the rate at which the stomach and intestines move during digestion. It also increases the rate at which the stomach empties into the intestines and increases the strength of the lower esophageal sphincter (the muscle between the stomach and esophagus).
- Metoclopramide is used to treat diabetic gastric stasis (slow movement of the stomach), which causes symptoms such as nausea, vomiting, heartburn, decreased appetite, and prolonged fullness after eating. It is also used to treat gastric reflux or heartburn (the regurgitation of stomach acid into the esophagus), prevention of postoperative nausea and vomiting, prevention of nausea and vomiting associated with cancer chemotherapy, facilitation of small bowel intubation, and to facilitate x-ray examination of the stomach and intestines.
- Metoclopramide may also be used for purposes other than those listed in this medication guide.
What should I discuss with my healthcare provider before taking metoclopramide?
- Do not take metoclopramide if you have
- bleeding, an injury, or an obstruction in your stomach;
- pheochromocytoma; or
- epilepsy or another seizure disorder.
- These conditions make it dangerous to use metoclopramide.
- Before taking this medication, tell your doctor if you have
- kidney disease;
- a history of depression;
- Parkinson's disease;
- diabetes;
- high blood pressure; or
- recently had stomach surgery.
- You may not be able to take metoclopramide, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
- Metoclopramide is in the FDA pregnancy category B. This means that it is unlikely to harm an unborn baby. Do not take metoclopramide without first talking to your doctor if you are pregnant.
- Metoclopramide passes into breast milk. Do not take metoclopramide without first talking to your doctor if you are breast-feeding a baby.
How should I take metoclopramide?
- Take metoclopramide exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
- Take each dose with a full glass of water.
- To ensure that you get a correct dose, measure the liquid form of metoclopramide with a special dose-measuring spoon or cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.
- Metoclopramide is available as both a syrup and a concentrated solution. Although the dose remains the same, the amount of liquid needed to make a dose is different. Follow your doctor's instructions.
- Metoclopramide is usually taken four times a day, 30 minutes before meals and at bedtime. Follow your doctor's instructions.
- Store metoclopramide at room temperature away from moisture and heat.
What happens if I miss a dose?
- Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.
What happens if I overdose?
- Seek emergency medical attention.
- Symptoms of a metoclopramide overdose include drowsiness; confusion; uncontrollable movements of the arms, legs, face, or tongue; muscle spasm of the neck; tremor; irritability; and agitation.
What should I avoid while taking metoclopramide?
- Use caution when driving, operating machinery, or performing other hazardous activities. Metoclopramide may cause drowsiness. If you experience drowsiness, avoid these activities.
Please see the end of this document for relevant limitations, full details of our medication information supplier, and revision date or version number.