Information on Amiloride and How to Use It, Precautions and Other Medications to Avoid While Taking

This first section of our medication database entry focuses on basic drug characteristics, uses and benefits, while part two covers side effects, interactions and additional information.

Amiloride Consumer Information

AMILORIDE

Generic Name: amiloride (a MIH low ride)

Brand Names: Midamor

What is the most important information I should know about amiloride?

  • To reduce nighttime urination, take amiloride early in the day unless otherwise directed by your doctor.
  • Take amiloride with food or milk to lessen stomach upset.
  • Do not use salt substitutes or low-sodium milk products that contain potassium while taking amiloride. These products could cause high levels of potassium in your blood. Ask your doctor or pharmacist about any salt substitutes you are taking.

What is amiloride?

  • Amiloride is in a class of drugs called potassium-sparing diuretics (water pills). It is used to reduce the amount of fluid in the body without causing the loss of potassium.
  • Amiloride is used to treat edema (swelling) and hypertension (high blood pressure).
  • Amiloride may also be used for purposes other than those listed in this medication guide.

Who should not take amiloride?

  • Before taking amiloride, tell your doctor if you
    • have kidney disease;
    • have liver disease;
    • have diabetes mellitus;
    • have high levels of potassium in your blood; or
    • are taking a potassium supplement or an angiotensin-converting-enzyme inhibitor (ACE inhibitor) such as captopril (Capoten), benazepril (Lotensin), lisinopril (Prinivil, Zestril), enalapril (Vasotec), or others.
  • You may not be able to take amiloride, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
  • Amiloride is in the FDA pregnancy category B. This means that it is unlikely to harm an unborn baby. Do not take amiloride without first talking to your doctor if you are pregnant.
  • It is not known whether amiloride passes into breast milk. Do not take amiloride without first talking to your doctor if you are breast-feeding a baby.

How should I take amiloride?

  • Take amiloride exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
  • Take each dose with a full glass of water.
  • Take amiloride with food or milk to lessen stomach upset.
  • To reduce nighttime urination, take amiloride early in the day unless otherwise directed by your doctor.
  • Do not stop taking amiloride suddenly even if you feel better. Stopping suddenly could make your condition worse.
  • Store amiloride at room temperature away from moisture and heat.

What happens if I miss a dose?

  • Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the dose you missed and take only you next regularly scheduled dose as directed. Do not take a double dose of this medication.

What happens if I overdose?

  • Seek emergency medical attention.
  • Symptoms of an amiloride overdose include an irregular heartbeat, lethargy, fatigue, weakness, drowsiness, dizziness, confusion, shortness of breath, nausea, and vomiting.

What should I avoid while taking amiloride?

  • Do not use salt substitutes or low-sodium milk products that contain potassium while taking amiloride. These products could cause high levels of potassium in your blood. Ask your doctor or pharmacist about any salt substitutes you are taking.

Please see the end of this document for relevant limitations, full details of our medication information supplier, and revision date or version number.