Part Two of Lanoxin Information, Focusing on Side Effects, Discontinuation or Withdrawal Effects, and Additional Information

This second section of our medication database entry focuses on potential side effects, withdrawal or discontinuation effects, and additional information, while part one covers basic drug characteristics, uses and benefits.

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What are the possible side effects of digoxin?

  • If you experience any of the following serious side effects, stop taking digoxin and seek medical attention or contact your doctor immediately:
    • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
    • a severe headache, fainting, or extreme drowsiness or dizziness;
    • irregular heartbeats;
    • slow heartbeats (fewer than 60 beats per minute);
    • abnormally fast heartbeats;
    • vision changes (e.g., yellow-green or blurred vision);
    • hallucinations; or
    • abnormal or psychotic behavior.
  • If you experience any of the following less serious side effects, continue to take digoxin and talk to your doctor if you experience
    • decreased appetite and diarrhea;
    • unusual tiredness or weakness;
    • depression;
    • nausea or vomiting;
    • drowsiness or dizziness;
    • decreased sex drive; or
    • enlarged breasts in males.
  • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect digoxin?

  • Before taking digoxin, tell your doctor if you are taking any of the following medicines:
    • another medication for irregular heartbeats, such as quinidine (Quinidex, Quinora, Cardioquin, others), amiodarone (Cordarone), or propafenone (Rythmol);
    • an antacid or laxative that contains aluminum, magnesium, or kaolin-pectin such as Maalox, Rolaids, Mylanta, Milk of Magnesia, and others;
    • a beta-blocker such as atenolol (Tenormin), propranolol (Inderal), acebutolol (Sectral), metoprolol (Lopressor), carteolol (Cartrol), labetalol (Normodyne, Trandate), or nadolol (Corgard);
    • a calcium channel blocker such as diltiazem (Cardizem, Dilacor XR, Tiazac), amlodipine (Norvasc), felodipine (Plendil), nifedipine (Procardia, Adalat), verapamil (Verelan, Calan, Isoptin, Covera-HS), and others;
    • a cancer chemotherapy drug;
    • a diuretic (water pill) such as hydrochlorothiazide (HCTZ, HydroDiuril, others), chlorothiazide (Diuril), chlorthalidone (Hygroton, Thalitone), furosemide (Lasix), torsemide (Demadex), bumetanide (Bumex), ethacrynic acid (Edecrin), triamterene (Dyrenium, Maxzide, Dyazide), amiloride (Midamor), spironolactone (Aldactone), eplerenone (Inspra), and others;
    • a steroid medicine such as prednisone (Deltasone), methylprednisolone (Medrol, others), prednisolone (Prelone, Pediapred, others), dexamethasone (Decadron), and others;
    • a thyroid medication;
    • alprazolam (Xanax);
    • amphotericin B (Fungizone);
    • cholestyramine (Questran, Prevalite) or colestipol (Colestid);
    • erythromycin (E.E.S., E-Mycin, Eryc, Ery-Tab, PCE, others) or clarithromycin (Biaxin);
    • indomethacin (Indocin);
    • itraconazole (Sporanox);
    • metoclopramide (Reglan);
    • rifampin (Rifadin, Rimactane);
    • sulfasalazine (Azulfidine); or
    • tetracycline (Broadspec, Emtet, Panmycin, Sumycin, Tetracap, others).
  • You may require a dosage adjustment or special monitoring if you are taking any of the medicines listed above.
  • Drugs other than those listed here may also interact with digoxin or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.

Where can I get more information?

  • Your pharmacist has additional information about digoxin written for health professionals that you may read.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Limitations and the Source of Our Online Medication Information Database

Although we have made considerable efforts to ensure that the information provided here is accurate, up-to-date, and complete, MedLibrary.org makes no guarantee to that effect. Drug information contained herein may be time sensitive. This medication information does not endorse drugs, diagnose patients or recommend any specific pharmacotherapy. This is an educational resource only -- intended to supplement but not to replace the expertise, skill, knowledge and judgment of medically qualified healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, please check with your doctor, nurse or local pharmacist. MedLibrary.org does not assume any responsibility for any aspect of healthcare administered with the aid of information provided here.

Full public license and copyright information is available separately from Cerner Multum, Inc.

Version: 6.02. Revision Date: 2/14/03.

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