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What are the possible side effects of phytonadione?

• Seek emergency medical attention or contact your doctor immediately if you experience any serious side effects from phytonadione such as:
• an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
• dizziness;
• fast or irregular heartbeats; or
• increased sweating.
• Other less serious side effects may be more likely to occur. Continue to use phytonadione and talk to your doctor if you experience
• flushing of the face;
• an unusual taste in the mouth; or
• pain or irritation at the injection site (injectable form).
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that is unusual or that is especially bothersome.

What other drugs will affect phytonadione?

• Before taking phytonadione, tell your doctor about all other medicines you are taking, especially any of the following:
• warfarin (Coumadin);
• mineral oil;
• orlistat (Xenical);
• cholestyramine (Questran, Prevalite);
• a salicylate such as aspirin (Acuprin, Ecotrin, Ascriptin, Bayer, others); choline salicylate and/or magnesium salicylate (Magan, Doan's, Bayer Select Backache Pain Formula, Mobidin, Arthropan, Trilisate, Tricosal), or salsalate (Disalcid);
• a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin, Advil, Nuprin, others), ketoprofen (Orudis, Orudis KT, Oruvail), naproxen (Naprosyn, Anaprox, Aleve), diclofenac (Voltaren, Cataflam), nabumetone (Relafen), oxaprozin (Daypro), piroxicam (Feldene), etodolac (Lodine), fenoprofen (Nalfon), flurbiprofen (Ansaid), indomethacin (Indocin), ketorolac (Toradol), sulindac (Clinoril), or tolmetin (Tolectin); or
• an antibiotic.
• You may not be able to take phytonadione, or you may require a dosage adjustment or special monitoring during treatment.
• Medications other than those listed here may also interact with phytonadione. Tell your doctor about all other prescription and over-the-counter medicines that you take, including vitamins, minerals, and herbal products.

Where can I get more information?

• Your pharmacist has more information about phytonadione written for health professionals that you may read.
• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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Although we have made considerable efforts to ensure that the information provided here is accurate, up-to-date, and complete, MedLibrary.org makes no guarantee to that effect. Drug information contained herein may be time sensitive. This medication information does not endorse drugs, diagnose patients or recommend any specific pharmacotherapy. This is an educational resource only -- intended to supplement but not to replace the expertise, skill, knowledge and judgment of medically qualified healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, please check with your doctor, nurse or local pharmacist. MedLibrary.org does not assume any responsibility for any aspect of healthcare administered with the aid of information provided here.

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Version: 1.02. Revision date: 8/18/03.