Normosol-R and Dextrose (Page 3 of 4)
DOSAGE AND ADMINISTRATION
Normosol-R and 5% Dextrose Injection is administered by intravenous infusion. The amount to be infused is based on replacement of losses of extracellular fluid volume in the individual patient. Up to 3 times the volume of estimated blood loss during and after surgery can be given to correct circulatory volume when there is only a moderate loss of blood.
As reported in the literature, the dosage and constant infusion rate of intravenous dextrose must be selected with caution in pediatric patients, particularly neonates and low birth weight infants, because of the increased risk of hyperglycemia/hypoglycemia.
Drug Interactions
Additives may be incompatible. Consult with pharmacist, if available. When introducing additives, use aseptic technique, mix thoroughly and do not store.
Normosol-R and 5% Dextrose solution does not contain calcium to avoid precipitation of calcium salts that may occur when certain drugs are added.
Parenteral drug products should be inspected visually for particulate matter or discoloration prior to administration, whenever solution and container permit. (See PRECAUTIONS.)
INSTRUCTIONS FOR USE
To Open:
Tear outer wrap at notch and remove solution container. Some opacity of the plastic due to moisture absorption during the sterilization process may be observed. This is normal and does not affect the solution quality or safety. If supplemental medication is desired, follow directions below before preparing for administration.
To Add Medication
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Prepare additive port.
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Using aseptic technique and an additive delivery needle of appropriate length, puncture resealable additive port at target area, inner diaphragm and inject. Withdraw needle after injecting medication.
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The additive port may be protected by covering with an additive cap.
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Mix container contents thoroughly.
To Administer
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Attach administration set per manufacturer’s instructions.
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Regulate rate of administration per institutional policy.
WARNING: Do not use flexible container in series connections.
HOW SUPPLIED
Normosol-R and 5% Dextrose Injection (Multiple Electrolytes and 5% Dextrose Injection Type 1, USP) is supplied in a 1000 mL single-dose flexible plastic container (NDC No. 0409–7968–09).
| TABLE | ||||||||||
| Electrolyte Content, Caloric Value and Characteristics | ||||||||||
| Milliequivalents per Liter | ||||||||||
| HC0 - 3 (alternates) | Cal* | mOsmol/L | Tonicity | |||||||
| Na + | K + | Mg ++ | Cl - | Acetate | Gluconate | per Liter | (calc.) | (total contents) | pH | |
| Normosol-R and 5% Dextrose | 140 | 5 | 3 | 98** | 27 | 23 | 185 | 547 | Hypertonic | 5.2 (4.0 to 6.5) |
* Normosol-R and 5% Dextrose calories derived from dextrose (170) and gluconate (15).
**Not including hydrochloric acid.
Store at 20 to 25°C (68 to 77°F). [See USP Controlled Room Temperature.] Protect from freezing.
® Normosol − multiple electrolyte solution, Hospira
Revised: May, 2009
Printed in USA
EN-2133
Hospira, Inc., Lake Forest, IL 60045 USA
