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| 1,2,4-Triazole | |
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| IUPAC name | 1H-1,2,4-triazole |
| Other names | 1,2,4-triazole pyrrodiazole |
| Identifiers | |
| CAS number | 288-88-0 |
| PubChem | |
| SMILES |
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| Properties | |
| Molecular formula | C2H3N3 |
| Molar mass | 69.0654 |
| Appearance | white solid |
| Melting point |
120-121 |
| Boiling point |
260 |
| Solubility in water | very soluble |
| Acidity (pKa) | 2.2 |
| Basicity (pKb) | 10.3 |
| Hazards | |
| Flash point | 140 |
| Related compounds | |
| Related compounds | 1,2,3-triazole imidazole |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox references |
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1,2,4-Triazole is one of a pair of isomeric chemical compounds with molecular formula C2H3N3, called triazoles, which have a five-membered ring of two carbon atoms and three nitrogen atoms. 1,2,4-Triazole is a basic aromatic heterocycle. 1,2,4-Triazole derivatives find use in a wide variety of applications, most notably as antifungals such as fluconazole and itraconazole.
1,2,4-Triazoles can be prepared using the Einhorn-Brunner reaction or the Pellizzari reaction.1
References
- ^ Potts K. T. (1961). "The Chemistry of 1,2,4-Triazoles.". Chemical Reviews 61 (2): 87–127. doi:.
Wikipedia content modification information:
- This page was last modified on 18 August 2008, at 18:20.
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