3F8

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3F8 is a murine, IgG31 monoclonal antibody which binds to GD2.2

It has been used in the detection and treatment of neuroblastoma.3<45

See also

References

  1. ^ Kushner BH, Cheung NK (1989). "GM-CSF enhances 3F8 monoclonal antibody-dependent cellular cytotoxicity against human melanoma and neuroblastoma". Blood 73 (7): 1936–41. PMID 2653466. http://www.bloodjournal.org/cgi/pmidlookup?view=long&pmid=2653466. 
  2. ^ "Sloan-Kettering - Neuroblastoma: 3F8 Monoclonal Antibody Therapy Q & A". Retrieved on 2008-02-19.
  3. ^ "ACS :: New Drug Targets Tough
    Childhood Cancer    ". Retrieved on 2008-02-19.
  4. ^ Yeh SD, Larson SM, Burch L, et al (1991). "Radioimmunodetection of neuroblastoma with iodine-131-3F8: correlation with biopsy, iodine-131-metaiodobenzylguanidine and standard diagnostic modalities". J. Nucl. Med. 32 (5): 769–76. PMID 1902508. http://jnm.snmjournals.org/cgi/pmidlookup?view=long&pmid=1902508. 
  5. ^ Dauer LT, St Germain J, Williamson MJ, et al (2007). "Whole-body clearance kinetics and external dosimetry of 131I-3F8 monoclonal antibody for radioimmunotherapy of neuroblastoma". Health Phys 92 (1): 33–9. doi:10.1097/01.HP.0000231583.32904.6c. PMID 17164597. http://meta.wkhealth.com/pt/pt-core/template-journal/lwwgateway/media/landingpage.htm?an=00004032-200701000-00005. 
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  • This page was last modified on 2 October 2008, at 02:45.

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