8-OH-DPAT

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8-OH-DPAT
Systematic (IUPAC) name
8-Hydroxy-2-(di-n-propylamino)tetralin
Identifiers
CAS number 78950-78-4
ATC code  ?
PubChem 1220
Chemical data
Formula C16H25NO 
Mol. mass 247.38 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?
Legal status
Routes  ?

8-OH-DPAT (8-hydroxy-2-(di-n-propylamino)tertraline) is a substance which acts as an agonist of the 5HT1A and 5HT7 receptors.[1]

It can elicit pelvic floor contractions.[2]

References

  1. ^ Schuhler S, Saboureau M, Pitrosky B, Pévet P (October 1998). "In Syrian hamsters, 5-HT fibres within the suprachiasmatic nuclei are necessary for the expression of 8-OH-DPAT induced phase-advance of locomotor activity rhythm". Neurosci. Lett. 256 (1): 33–6. doi:10.1016/S0304-3940(98)00749-6. PMID 9832210. 
  2. ^ Thomas CA, Tyagi S, Yoshimura N, Chancellor MB, Tyagi P (October 2007). "Effect of hyperforin-enriched extract on pro-ejaculatory effect of 8-hydroxy-2-(di-N-propylamino)tetralin in anesthetized rats". Urology 70 (4): 813–6. doi:10.1016/j.urology.2007.05.016. PMID 17991578. 
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