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ATP-binding cassette, sub-family F (GCN20), member 2
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| Identifiers | ||||||||||||||
| Symbols | ABCF2; ABC28; DKFZp586K1823; EST133090; HUSSY-18; M-ABC1 | |||||||||||||
| External IDs | MGI: 1351657 HomoloGene: 21408 | |||||||||||||
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| RNA expression pattern | ||||||||||||||
| Orthologs | ||||||||||||||
| Human | Mouse | |||||||||||||
| Entrez | 10061 | 27407 | ||||||||||||
| Ensembl | ENSG00000033050 | ENSMUSG00000028953 | ||||||||||||
| Uniprot | Q9UG63 | Q3UVI9 | ||||||||||||
| Refseq | NM_005692 (mRNA) NP_005683 (protein) |
NM_013853 (mRNA) NP_038881 (protein) |
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| Location | Chr 7: 150.54 - 150.56 Mb | Chr 5: 24.08 - 24.09 Mb | ||||||||||||
| Pubmed search | [1] | [2] | ||||||||||||
ATP-binding cassette, sub-family F (GCN20), member 2, also known as ABCF2, is a human gene.[1]
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This protein is a member of the GCN20 subfamily. Alternative splicing of this gene results in multiple transcript variants.[1]
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See also
References
Further reading
- Klein I, Sarkadi B, Váradi A (2000). "An inventory of the human ABC proteins.". Biochim. Biophys. Acta 1461 (2): 237–62. PMID 10581359.
- Dean M, Rzhetsky A, Allikmets R (2001). "The human ATP-binding cassette (ABC) transporter superfamily.". Genome Res. 11 (7): 1156–66. doi:. PMID 11435397.
- Allikmets R, Gerrard B, Hutchinson A, Dean M (1997). "Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.". Hum. Mol. Genet. 5 (10): 1649–55. PMID 8894702.
- Hogue DL, Liu L, Ling V (1999). "Identification and characterization of a mammalian mitochondrial ATP-binding cassette membrane protein.". J. Mol. Biol. 285 (1): 379–89. doi:. PMID 9878413.
- Zhang F, Hogue DL, Liu L, et al. (2000). "M-ABC2, a new human mitochondrial ATP-binding cassette membrane protein.". FEBS Lett. 478 (1-2): 89–94. PMID 10922475.
- Ye Z, Connor JR (2000). "cDNA cloning by amplification of circularized first strand cDNAs reveals non-IRE-regulated iron-responsive mRNAs.". Biochem. Biophys. Res. Commun. 275 (1): 223–7. doi:. PMID 10944468.
- Stanchi F, Bertocco E, Toppo S, et al. (2001). "Characterization of 16 novel human genes showing high similarity to yeast sequences.". Yeast 18 (1): 69–80. doi:. PMID 11124703.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:. PMID 12477932.
- Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology.". Science 300 (5620): 767–72. doi:. PMID 12690205.
- Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7.". Nature 424 (6945): 157–64. doi:. PMID 12853948.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:. PMID 15489334.
- Tsuda H, Ito YM, Ohashi Y, et al. (2006). "Identification of overexpression and amplification of ABCF2 in clear cell ovarian adenocarcinomas by cDNA microarray analyses.". Clin. Cancer Res. 11 (19 Pt 1): 6880–8. doi:. PMID 16203778.
- Nishimura S, Tsuda H, Ito K, et al. (2007). "Differential expression of ABCF2 protein among different histologic types of epithelial ovarian cancer and in clear cell adenocarcinomas of different organs.". Hum. Pathol. 38 (1): 134–9. doi:. PMID 16996567.
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Wikipedia content modification information:
- This page was last modified on 10 July 2008, at 03:27.
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