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Accession number may mean:
- Accession number (bioinformatics), a unique identifier given to a biological polymer sequence (DNA, protein) when it is submitted to a sequence database.
- Accession number (library science), the unique number given to each new acquisition as it is entered in the catalog of a library or museum.
- Accession number (medicine), a unique identifier for an order, used in medical information systems like a LIS or RIS. Image data generated as a response to the order usually contain the accession number, making it possible to link images with orders.