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Aceclidine
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| Systematic (IUPAC) name | |
| 1-azabicyclo[2.2.2]oct-8-yl acetate | |
| Identifiers | |
| CAS number | (or 6109-70-2 [HCl]) |
| ATC code | S01 |
| PubChem | |
| ChemSpider | |
| Chemical data | |
| Formula | C9H15NO2 |
| Mol. mass | 169.221 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status |
℞ Prescription only |
| Routes | Ocular |
Aceclidine (INN) (trade names Glaucostat, Glaunorm, Glaudin) is a parasympathomimetic miotic agent used in the treatment of narrow angle glaucoma. It decreases intraocular pressure.
Mechanism of action
Aceclidine acts primarily on the muscarinic receptor.[1]
Side effects
Side effects of aceclidine include increased salivation, bradycardia (in excessive doses).
References
- ^ Shannon HE, Hart JC, Bymaster FP, et al (August 1999). "Muscarinic receptor agonists, like dopamine receptor antagonist antipsychotics, inhibit conditioned avoidance response in rats". J. Pharmacol. Exp. Ther. 290 (2): 901–7. PMID 10411607.
- ACECLIDINE CHLORHYDRATE [Article in French] Biam. Last update: 2 September 1999. Accessed 13 September 2005 (UTC)
- ACECLIDINE (АЦЕКЛИДИН) [Article in Russian] ViDAL 2005. Accessed 13 September 2005.
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Wikipedia content modification information:
- This page was last modified on 9 September 2008, at 04:50.
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