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Afloqualone
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| Systematic (IUPAC) name | |
| 6-amino-2-(fluoromethyl)-3-(2-methylphenyl)quinazolin-4-one | |
| Identifiers | |
| CAS number | |
| ATC code | ? |
| PubChem | |
| Chemical data | |
| Formula | C16H14FN3O |
| Mol. mass | 283.3 |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | ? |
Afloqualone (Arofuto) is an analogue of methaqualone developed in the 1980s in Japan. It has sedative and muscle relaxant effects,[1] and has had some clinical use, although it causes photosensitization as a side effect which can cause skin problems such as dermatitis.[2]
See also
References
- ^ Ochiai T, Ishida R. Pharmacological studies on 6-amino-2-fluoromethyl-3-(O-tolyl)-4(3H)-quinazolinone (afloqualone), a new centrally acting muscle relaxant. (II) Effects on the spinal reflex potential and the rigidity. Japanese Journal of Pharmacology. 1982 Jun;32(3):427-38.
- ^ Ishikawa T, Kamide R, Niimura M. Photoleukomelanodermatitis (Kobori) induced by afloqualone. Journal of Dermatology. 1994 Jun;21(6):430-3.
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- This page was last modified on 16 September 2007, at 11:55.
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