Aprobarbital

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Aprobarbital
Systematic (IUPAC) name
5-propan-2-yl-5-prop-2-enyl-1,3-diazinane-2,4,6-trione
Identifiers
CAS number 77-02-1
ATC code N05CA05
PubChem 6464
Chemical data
Formula C10H14N2O3 
Mol. mass 210.23 g/mol
Synonyms Aprobarbital, Oramon, Allylpropymal, Alurate, 5-Isopropyl-5-allylbarbituric acid
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?
Legal status
Routes  ?

Aprobarbital (Oramon) is a barbiturate derivative invented in the 1920s by Ernst Preiswerk. It has sedative, hypnotic and anticonvulsant properties, and was used primarily for the treatment of insomnia. [1] Aprobarbital was never as widely used as more common barbiturate derivatives such as phenobarbital and is now rarely prescribed as it has been replaced by newer drugs with a better safety margin.


References

  1. ^ Reddemann H, Turk E. Oramon poisoning in infancy and childhood. Observations on 12 aprobarbital poisonings (German). Das Deutsche Gesundheitswesen. 1966 May 12;21(19):878-81.
Space-filling model of phenobarbital, the most widely-used anticonvulsant in the world  This anticonvulsant-related article is a stub. You can help Wikipedia by expanding it.
 This sedative-related article is a stub. You can help Wikipedia by expanding it.
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Barbiturates (N01AF, N03AA, N05CA)

Allobarbital • Alphenal • Amobarbital • Aprobarbital • Barbexaclone • Barbital • Brallobarbital • Brophebarbital • Bucolome • Butabarbital • Butalbital • Butobarbital • Butallylonal • Crotylbarbital • Cyclobarbital • Cyclopal • Enallylpropymal • Ethallobarbital • Febarbamate • Heptabarbital • Hexethal • Hexobarbital • Mephobarbital • Metharbital • Methohexital • Methylphenobarbital • Narcobarbital • Nealbarbital • Pentobarbital • Phenobarbital • Phetharbital • Prazitone • Probarbital • Propallylonal • Proxibarbal • Proxibarbital • Reposal • Secbutabarbital • Secobarbital • Sigmodal • Spirobarbital • Talbutal • Thialbarbital • Thiamylal • Thiobarbital • Thiobutabarbital • Thiopental • Valofane • Vinbarbital • Vinylbital
v • d • e
Psycholeptics: hypnotics and sedatives (N05C)
GABAA receptor
Alpha-2 adrenergic receptor
Melatonin receptor
Histamine receptor &
Acetylcholine receptor
GABAB receptor / GHB receptor
GHB Type
Other receptors/
ungrouped
Other

Wikipedia content modification information:

  • This page was last modified on 19 January 2008, at 01:27.

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