This MedLibrary.org supplementary page on Aspergillus fumigatus is provided directly from the open source Wikipedia as a service to our readers. Please see the note below on authorship of this content, as well as the Wikipedia usage guidelines. To search for other content from our encyclopedia supplement, please use the form below:
Related Sponsors
| Aspergillus fumigatus | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 Aspergillus fumigatus
|
||||||||||||||
| Scientific classification | ||||||||||||||
|
||||||||||||||
| Binomial name | ||||||||||||||
| Aspergillus fumigatus Fresenius 1863 |
Aspergillus fumigatus is a fungus of the genus Aspergillus, and is one of the most common Aspergillus species to cause disease in immunocompromised individuals.
A. fumigatus has a stable haploid genome, with no known sexual cycle, and reproduces by forming conidiospores that are released into the environment. Capable of growth at 37°C (human body temperature), spores are common inhalation pollutants; typically, however, these are quickly eliminated by the immune system in healthy individuals.
When the fermentation broth of A. fumigatus was screened, a number of indolic alkaloids with anti-mitotic properties were discovered.1 The compounds of interest have been of a class known as tryprostatins, with spirotryprostatin B being of special interest as an anti-cancer drug.
Genome
The genome sequences of three Aspergillus species—Aspergillus fumigatus, Aspergillus nidulans, and Aspergillus oryzae—were published in the journal Nature in December 2005.234
Gallery
 |
 Conidia phialoconidia of Aspergillus fumigatus |
 Colony in Petri dish |
 Aspergillus fumigatus isolated from woodland soil |
See also
References
- ^ Cui CB et al (1996). "Spirotryprostatin B, a novel mammalian cell cycle inhibitor produced by Aspergillus fumigatus". J. Antibiot. 49: 832–835. PMID 8823522.
- ^ Galagan JE et al (2005). "Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae". Nature 438 (7071): 1105–15. doi:. PMID 16372000.
- ^ Nierman WC et al (2005). "Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus". Nature 438 (7071): 1151–6. doi:. PMID 16372009.
- ^ Machida M et al (2005). "Genome sequencing and analysis of Aspergillus oryzae". Nature 438 (7071): 1157–61. doi:. PMID 16372010.
External links
- Emergence of Azole Resistance in Aspergillus fumigatus and Spread of a Single Resistance Mechanism. at SciVee
- The Aspergillus Trust A registered UK charity engaged in support of sufferers of aspergillus disease worldwide and research into cures
- The Fungal Research Trust
- Aspergillus info from DoctorFungus.org
 |
This Ascomycota-related article is a stub. You can help Wikipedia by expanding it. |
Wikipedia content modification information:
- This page was last modified on 19 November 2008, at 04:13.
Wikipedia Authorship and Review
Wikipedia content provided here is not reviewed directly by MedLibrary.org. Wikipedia content is authored by an open community of volunteers and is not produced by or in any way affiliated with MedLibrary.org.
Wikipedia Usage Guidelines
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article on "Aspergillus fumigatus".
The URL for this specific entry is:
All Wikipedia text is available under the terms of the GNU Free Documentation License. (See Copyrights for details). Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc.