This MedLibrary.org supplementary page on Auer rod is provided directly from the open source Wikipedia as a service to our readers. Please see the note below on authorship of this content, as well as the Wikipedia usage guidelines. To search for other content from our encyclopedia supplement, please use the form below:
Related Sponsors
Auer rods can be seen in the leukemic blasts of Acute Myeloid Leukemia. Auer rods are clumps of azurophilic granular material that form elongated needles seen in the cytoplasm of leukemic blasts. They are composed of fused lysosomes and contain peroxidase, lysosomal enzymes, and large crystalline inclusions.
Auer rods are classically seen in myeloid blasts of M1, M2, M3, and M4 acute leukemias.
They are also used to distinguish the pre-leukemia Myelodysplastic Syndromes: Refractory Anemia with Excess Blasts 2 (which has Auer rods) from RAEB 1 (which does not).
Eponym
These cytoplasmic inclusions are named for John Auer, an American physiologist (1875-1948).1
References
- ^ Auer, John (1906). "Some hitherto undescribed structures found in the large lymphocytes of a case of acute leukaemia". American Journal of the Medical Sciences 131 (6): 1002–1015. ISSN 00029629.
External links
- Overview at University of Virginia
- Image at NIH/MedlinePlus
- Slides at wadsworth.org
- Image at University of Utah
|
|||||
|
|||||
_histopatholgy.jpg){kind=small} |
This article related to pathology is a stub. You can help Wikipedia by expanding it. |
Wikipedia content modification information:
- This page was last modified on 28 September 2008, at 12:50.
Wikipedia Authorship and Review
Wikipedia content provided here is not reviewed directly by MedLibrary.org. Wikipedia content is authored by an open community of volunteers and is not produced by or in any way affiliated with MedLibrary.org.
Wikipedia Usage Guidelines
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article on "Auer rod".
The URL for this specific entry is:
All Wikipedia text is available under the terms of the GNU Free Documentation License. (See Copyrights for details). Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc.