Bambuterol

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Bambuterol
Systematic (IUPAC) name
{3-(dimethylcarbamoyloxy)-5-[1-hydroxy-2-(tert-butylamino)
ethyl]phenyl} N,N-dimethylcarbamate
Identifiers
CAS number 81732-46-9
ATC code R03CC12
PubChem 54766
Chemical data
Formula C18H29N3O5 
Mol. mass 367.44 g/mol
Pharmacokinetic data
Bioavailability 20%
Metabolism Hepatic, extensive
Further metabolized to terbutaline by plasma cholinesterase
Half life 13 hours (bambuterol)
21 hours (terbutaline)
Excretion Renal
Therapeutic considerations
Pregnancy cat.

Unknown
Legal status

℞ Prescription only
Routes Oral

Bambuterol (INN, marketed by AstraZeneca under the trade names Bambec and Oxeol) is a long acting beta-adrenoceptor agonist used in the treatment of asthma. It is a prodrug of terbutaline.


v • d • e
Adrenergic agonists (models/most important in CAPS)
α
β
Nonselective β
α and β
Epinephrine (α1+2, β1+2) · Norepinephrine (α1+2, β1) · Cirazoline · Etilefrine
Indirect/
mixed
Indirect (presynaptic norepinephrine release): Amphetamine · Tyramine

Mixed: Ephedrine · Pseudoephedrine

Cocaine
v • d • e
Drugs for obstructive airway diseases: asthma/COPD (R03)
Adrenergics, inhalants
Arformoterol • Bambuterol • Clenbuterol • Formoterol • Salmeterol Ultra LABA: Indacaterol
other
Glucocorticoids
Anticholinergics/
muscarinic antagonist
Mast cell stabilizers
Xanthines
Leukotriene antagonists
Lipoxygenase inhibitor
Thromboxane receptor antagonists
Combination products
Tablets  This pharmacology-related article is a stub. You can help Wikipedia by expanding it.

Wikipedia content modification information:

  • This page was last modified on 19 July 2008, at 21:18.

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