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Benactyzine
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| Systematic (IUPAC) name | |
| 2-diethylaminoethyl 2-hydroxy-2,2-di(phenyl)acetate | |
| Identifiers | |
| CAS number | |
| ATC code | ? |
| PubChem | |
| Chemical data | |
| Formula | C20H25NO3 |
| Mol. mass | 327.42 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
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| Legal status | |
| Routes | ? |
Benactyzine is an anticholinergic drug. It is a glycolic acid ester, related to other drugs such as the piperidinyl benzilates and 3-Quinuclidinyl benzilate but with much less potent anticholinergic effects.
Benactyzine has been used as an antidepressant,[1] however its use for this application is limited by anticholinergic side effects such as dry mouth and nausea, and at high doses it can cause more severe symptoms such as deliriant and hallucinogenic effects. Consequently it is no longer widely used in medicine, although it is still a useful drug for scientific research.
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References
- ^ McLaughlin B, Rickels K, Abidi M, Toro R. Meprobamate-benactyzine (Deprol) and placebo in two depressed outpatient populations. Psychosomatics. 1969 Mar-Apr;10(2):73-81.
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Wikipedia content modification information:
- This page was last modified on 1 December 2007, at 07:42.
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