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Bismuth subsalicylate
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| Systematic (IUPAC) name | |
| 2-Hydroxy-4H-1,3,2-benzodioxabismin-4-one | |
| Identifiers | |
| CAS number | |
| ATC code | ? |
| PubChem | |
| Chemical data | |
| Formula | C7H5BiO4 |
| Mol. mass | 362.11 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | ? |
Bismuth subsalicylate, with a chemical formula C7H5BiO4,[1] is a drug used to treat nausea, heartburn, indigestion, upset stomach, diarrhea, and other temporary discomforts of the stomach and gastrointestinal tract. It is the active ingredient in popular medications such as Pepto-Bismol and (modern) Kaopectate.
As a salt of salicylic acid, bismuth salicylate displays anti-inflammatory action and also acts as an antacid.
It can also cause a black tongue and black stools in some users of the drug, when it combines with trace amounts of sulfur in their saliva and gastrointestinal tract.[2] This discoloration is temporary and harmless.
Children should not take medication with bismuth subsalicylate while recovering from influenza or chicken pox, as epidemiologic evidence points to an association between the use of salicylate-containing medications during certain viral infections and the onset of Reye's syndrome.[3]
References
- ^ Merck Index, 11th Edition, 1299.
- ^ Drug information page at the National Institutes of Health
- ^ Aspirin or Salicylate-Containing Medications, reyessyndrome.org
Wikipedia content modification information:
- This page was last modified on 31 May 2008, at 20:06.
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