CACNB3

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Calcium channel, voltage-dependent, beta 3 subunit
PDB rendering based on 1vyt.
Available structures: 1vyt, 1vyu
Identifiers
Symbols CACNB3; CACNLB3
External IDs OMIM: 601958 MGI: 103307 HomoloGene: 20187
RNA expression pattern

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More reference expression data
Orthologs
Human Mouse
Entrez 784 12297
Ensembl ENSG00000167535 ENSMUSG00000003352
Uniprot P54284 Q8K5A7
Refseq NM_000725 (mRNA)
NP_000716 (protein)		 NM_001044741 (mRNA)
NP_001038206 (protein)
Location Chr 12: 47.5 - 47.51 Mb Chr 15: 98.46 - 98.47 Mb
Pubmed search [1] [2]

Calcium channel, voltage-dependent, beta 3 subunit, also known as CACNB3, is a human gene.[1]


Contents

See also

References

  1. ^ "Entrez Gene: CACNB3 calcium channel, voltage-dependent, beta 3 subunit".

Further reading

  • Yamada Y, Masuda K, Li Q, et al. (1995). "The structures of the human calcium channel alpha 1 subunit (CACNL1A2) and beta subunit (CACNLB3) genes.". Genomics 27 (2): 312–9. doi:10.1006/geno.1995.1048. PMID 7557998. 
  • Collin T, Lory P, Taviaux S, et al. (1994). "Cloning, chromosomal location and functional expression of the human voltage-dependent calcium-channel beta 3 subunit.". Eur. J. Biochem. 220 (1): 257–62. PMID 8119293. 
  • Rosenfeld MR, Wong E, Dalmau J, et al. (1993). "Cloning and characterization of a Lambert-Eaton myasthenic syndrome antigen.". Ann. Neurol. 33 (1): 113–20. doi:10.1002/ana.410330126. PMID 8494331. 
  • Murakami M, Wissenbach U, Flockerzi V (1996). "Gene structure of the murine calcium channel beta3 subunit, cDNA and characterization of alternative splicing and transcription products.". Eur. J. Biochem. 236 (1): 138–43. PMID 8617257. 
  • Scott VE, De Waard M, Liu H, et al. (1996). "Beta subunit heterogeneity in N-type Ca2+ channels.". J. Biol. Chem. 271 (6): 3207–12. PMID 8621722. 
  • Bell DC, Butcher AJ, Berrow NS, et al. (2001). "Biophysical properties, pharmacology, and modulation of human, neuronal L-type (alpha(1D), Ca(V)1.3) voltage-dependent calcium currents.". J. Neurophysiol. 85 (2): 816–27. PMID 11160515. 
  • Colecraft HM, Alseikhan B, Takahashi SX, et al. (2002). "Novel functional properties of Ca(2+) channel beta subunits revealed by their expression in adult rat heart cells.". J. Physiol. (Lond.) 541 (Pt 2): 435–52. PMID 12042350. 
  • Murakami M, Fleischmann B, De Felipe C, et al. (2002). "Pain perception in mice lacking the beta3 subunit of voltage-activated calcium channels.". J. Biol. Chem. 277 (43): 40342–51. doi:10.1074/jbc.M203425200. PMID 12161429. 
  • Qin N, Yagel S, Momplaisir ML, et al. (2002). "Molecular cloning and characterization of the human voltage-gated calcium channel alpha(2)delta-4 subunit.". Mol. Pharmacol. 62 (3): 485–96. PMID 12181424. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Chen YH, Li MH, Zhang Y, et al. (2004). "Structural basis of the alpha1-beta subunit interaction of voltage-gated Ca2+ channels.". Nature 429 (6992): 675–80. doi:10.1038/nature02641. PMID 15170217. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Vendel AC, Terry MD, Striegel AR, et al. (2006). "Alternative splicing of the voltage-gated Ca2+ channel beta4 subunit creates a uniquely folded N-terminal protein binding domain with cell-specific expression in the cerebellar cortex.". J. Neurosci. 26 (10): 2635–44. doi:10.1523/JNEUROSCI.0067-06.2006. PMID 16525042. 

External links

 This membrane protein-related article is a stub. You can help Wikipedia by expanding it.
v • d • e
Membrane transport protein: ion channels
Ca2+: Calcium channel
L-type/Cavα (1.1, 1.2, 1.3, 1.4) • N-type/Cavα2.2 • P-type/Cavα(2.1) • Q-type/Cavα2.1 • R-type/Cavα2.3 • T-type/Cavα(3.2)
α2δ-subunits (1, 2) • β-subunits (β1, β2, β3, β4) • γ-subunits (γ1, γ2, γ3, γ4)
Other
Na+: Sodium channel
Navα (1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8, 1.9, 7A) • Navβ (1, 2, 3, 4)
Other
K+: Potassium channel
Kvα (1-6) (1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.10, 2.1, 2.2, 3.1, 3.2, 3.3, 3.4, 4.1, 4.2, 4.3, 5.1, 6.1, 6.2, 6.3, 6.4)
Kvα (7-12) (7.1, 7.2, 7.3, 7.4, 7.5, 8.1, 8.2, 9.1, 9.2, 9.3, 10.1, 10.2, 11.1/hERG, 11.2, 11.3, 12.1, 12.2, 12.3)
Kvβ (1, 2, 3) • KCNIP (1, 2, 3, 4) • minK/ISK • MiRP (1, 2, 3) • Shaker gene
Kir (1.1, 2.1, 2.2, 2.3, 2.4) • GIRK/Kir (3.1, 3.2, 3.3, 3.4) • Kir (4.1, 4.2, 5.1, 6.1, 6.2, 7.1)
K2P (1, 2, 3, 4, 5, 6, 7, 9, 10, 12, 13, 15, 16, 17, 18)
M+: TRP cation channel
TRPA (1) • TRPC (1, 2, 3, 4, 4AP, 5, 6, 7) • TRPM (1, 2, 3, 4, 5, 6, 7, 8) • TRPML (1, 2, 3) • TRPP (1, 2) • TRPV (1, 2, 3, 4, 5, 6)
Cl-: Chloride channel
CFTR • CLCA (1, 2, 3, 4) • CLCN (1, 2, 3, 4, 5, 6, 7, KA, KB) • CLIC (1, 2, 3, 4, 5, 6) • CLNS (1A, 1B)
Cyclic nucleotide-gated
α1, α2, α3, α4, β1, β3, H1, H2, H3, H4
Porin
Other/general

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