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| Calsequestrin monomer showing the three repeating calsequestrin domains | |
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calsequestrin 1 (fast-twitch, skeletal muscle)
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| Identifiers | |
| Symbol | CASQ1 |
| Alt. Symbols | CASQ |
| Entrez | 844 |
| HUGO | 1512 |
| OMIM | 114250 |
| PDB | 1A8Y |
| RefSeq | NM_001231 |
| UniProt | P31415 |
| Other data | |
| Locus | Chr. 1 q21 |
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calsequestrin 2 (cardiac muscle)
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| Identifiers | |
| Symbol | CASQ2 |
| Entrez | 845 |
| HUGO | 1513 |
| OMIM | 114251 |
| RefSeq | NM_001232 |
| UniProt | O14958 |
| Other data | |
| Locus | Chr. 1 p13.3-p11 |
Calsequestrin is a calcium-binding protein of the sarcoplasmic reticulum. The protein helps hold calcium in the cisterna of the sarcoplasmic reticulum after a muscle contraction, even though the concentration of calcium in the sarcoplasmic reticulum is much higher than in the cytosol. It also helps sarcoplasmic reticulum store an amazing amount of calcium ions.
See also
External links
References
Wang S, Trumble WR, Liao H, Wesson CR, Dunker AK, Kang CH (1998). "Crystal structure of calsequestrin from rabbit skeletal muscle sarcoplasmic reticulum". Nat. Struct. Biol. 5 (6): 476–83. PMID 9628486.
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This article on a gene on chromosome 1 is a stub. You can help Wikipedia by expanding it. |
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The principle calcium - binding protein found in the Sarcoplasmic Reticulum which also provides calcium storage
Wikipedia content modification information:
- This page was last modified on 31 July 2008, at 01:50.
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