CXCL3

This MedLibrary.org supplementary page on CXCL3 is provided directly from the open source Wikipedia as a service to our readers. Please see the note below on authorship of this content, as well as the Wikipedia usage guidelines. To search for other content from our encyclopedia supplement, please use the form below:

Related Sponsors

BM Pharmacy Generic pharmaceuticals at unbeatable prices. Insomnia, men's health, hair health, pain control. bmpharmacy.com
Online Pharmacy Carisoprodol, tadalafil, sildenafil, vardenafil and more... xlpharmacy.com
MedBasket.com Discreet. Inexpensive. Fast shipping. Great selection. What more can we say? medbasket.com
Frugalmed 2000 reasons to shop with us first. frugalmed.com
Ads by Tiva

chemokine (C-X-C motif) ligand 3
Identifiers
Symbol CXCL3
Alt. Symbols SCYB3, GRO3, GROg, MIP-2b, CINC-2b
Entrez 2921
HUGO 4604
OMIM 139111
RefSeq NM_002090
UniProt P19876
Other data
Locus Chr. 4 q21

Chemokine (C-X-C motif) ligand 3 (CXCL3) is a small cytokine belonging to the CXC chemokine family that is also known as GRO3 oncogene (GRO3), GRO protein gamma (GROg) and macrophage inflammatory protein-2-beta (MIP2b). CXCL3 controls migration and adhesion of monocytes and mediates it effects on its target cell by interacting with a cell surface chemokine receptor called CXCR2.12 The gene for CXCL3 is located on chromosome 4 in a cluster of other CXC chemokines.3


References

  1. ^ Smith DF, Galkina E, Ley K, Huo Y. GRO family chemokines are specialized for monocyte arrest from flow. Am J Physiol Heart Circ Physiol. 2005, 289(5):H1976-84. PMID: 15937099
  2. ^ Ahuja SK, Murphy PM. The CXC chemokines growth-regulated oncogene (GRO) alpha, GRObeta, GROgamma, neutrophil-activating peptide-2, and epithelial cell-derived neutrophil-activating peptide-78 are potent agonists for the type B, but not the type A, human interleukin-8 receptor. J Biol Chem. 1996, 23;271(34):20545-50. PMID: 8702798
  3. ^ O'Donovan, N., Galvin, M. Morgan, J.G. Physical mapping of the CXC chemokine locus on human chromosome 4. Cytogenet. Cell Genet. 84: 39-42, 1999. PMID: 10343098


v • d • e
Cell signaling: cytokines
By family
IL-1 superfamily
1 (1Ra) · 18 · 33
IL-6 like/gp130 utilizing
IL-10 family
10 · 19 · 20 · 22 · 24 · 26
28 · 29
2/15 · 3 · 4 · 7 · 9 · 13 · 21
IL-12 family
12 · 23 · 27 · 35
Other
5 · 8 · 14 · 16 · 17/25 (A) · 32
CCL
1 · 2 · 3 · 4 · 5 · 6 · 7 · 8 · 9 · 10 · 11 · 12 · 13 · 14 · 15 · 16 · 17 · 18 · 19 · 20 · 21 · 22 · 23 · 24 · 25 · 26 · 27 · 28
CXCL
1 · 2 · 3 · 4 · 5 · 6 · 7 · 8 · 9 · 10 · 11 · 12 · 13 · 14 · 15 · 16 · 17
CX3CL
XCL
1 · 2
Main
TNF (ligand) superfamily
CD70 · CD153 · CD154
alpha (Pegylated 2a, Pegylated 2b), beta (1a, 1b)
28 · 29
Other
By function
 This article on a gene on chromosome 4 is a stub. You can help Wikipedia by expanding it.

Wikipedia content modification information:

  • This page was last modified on 6 May 2008, at 14:43.

Wikipedia Authorship and Review

Wikipedia content provided here is not reviewed directly by MedLibrary.org. Wikipedia content is authored by an open community of volunteers and is not produced by or in any way affiliated with MedLibrary.org.

Wikipedia Usage Guidelines

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article on "CXCL3".

The URL for this specific entry is:

All Wikipedia text is available under the terms of the GNU Free Documentation License. (See Copyrights for details). Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc.