Carboprost

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Carboprost
Systematic (IUPAC) name
(5Z,9α,11α,13E,15S)-9,11,15-trihydroxy-15- methylprosta-5,13-dien-1-oic acid
Identifiers
CAS number 58551-69-2
ATC code G02AD04
PubChem 5284525
DrugBank APRD00847
Chemical data
Formula C21H36O5 
Mol. mass 368.508 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?
Legal status

℞ Prescription only
Routes Intravenous

Carboprost ("carboprost tromethamine") is a synthetic prostaglandin analogue of 15-methyl-PGF2a with oxytocic properties. Can be used to induce labor or can trigger abortion in early pregnancy. It is e.g. used in mola hydatidosa. It is also used in the treatment of postpartum bleeding. Caution in asthmatic patients. The trade name is Hemabate

External links

  • MeSH Carboprost
  • Indman P (2004). "Use of carboprost to facilitate hysteroscopic resection of submucous myomas.". J Am Assoc Gynecol Laparosc 11 (1): 68–72. doi:10.1016/S1074-3804(05)60014-X. PMID 15104835. 
  • Vukelić J. "Second trimester pregnancy termination in primigravidas by double application of dinoprostone gel and intramuscular administration of carboprost tromethamine.". Med Pregl 54 (1-2): 11–6. PMID 11436877. 
  • Ippoliti C, Przepiorka D, Mehra R, Neumann J, Wood J, Claxton D, Gajewski J, Khouri I, van Besien K, Andersson B (1995). "Intravesicular carboprost for the treatment of hemorrhagic cystitis after marrow transplantation.". Urology 46 (6): 811–5. doi:10.1016/S0090-4295(99)80349-5. PMID 7502421. 
v • d • e
Eicosanoids: prostaglandins
Endogenous/series 2
Prostaglandin analogues
v • d • e
Oxytocics (G02A)
Ergot alkaloids
Prostaglandins
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Wikipedia content modification information:

  • This page was last modified on 28 June 2008, at 04:46.

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