Carteolol

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Carteolol
Systematic (IUPAC) name
5-[2-hydroxy-3- (tert-butylamino) propoxy]- 3,4-dihydro-1H-quinolin-2-one
Identifiers
CAS number 51781-06-7
ATC code C07AA15 S01ED05
PubChem 2583
DrugBank APRD00195
ChemSpider 2485
Chemical data
Formula C16H24N2O3 
Mol. mass 292.373 g/mol
Pharmacokinetic data
Bioavailability 85%
Metabolism Hepatic, active with 8-hydrocarteolol
Half life 6–8 hours
Excretion Renal (50-70%)
Therapeutic considerations
Pregnancy cat.

C(US)
Legal status
Routes oral

Carteolol (trade name Teoptic) is a beta blocker used to treat glaucoma.

External links

  • El-Kamel A, Al-Dosari H, Al-Jenoobi F. "Environmentally responsive ophthalmic gel formulation of carteolol hydrochloride.". Drug Deliv 13 (1): 55–9. doi:10.1080/10717540500309073. PMID 16401594. 
  • Kuwahara K, Oizumi N, Fujisawa S, Tanito M, Ohira A (2005). "Carteolol hydrochloride protects human corneal epithelial cells from UVB-induced damage in vitro.". Cornea 24 (2): 213–20. doi:10.1097/01.ico.0000141232.41343.9d. PMID 15725891. 
  • Trinquand C, Romanet J, Nordmann J, Allaire C (2003). "[Efficacy and safety of long-acting carteolol 1% once daily. A double-masked, randomized study]". J Fr Ophtalmol 26 (2): 131–6. PMID 12660585. 
v • d • e
Ophthalmologicals: antiglaucoma preparations and miotics (S01E)
Sympathomimetics
Parasympathomimetics
Carbonic anhydrase inhibitors
Beta blocking agents
Befunolol • Betaxolol • Carteolol • Levobunolol • Metipranolol • Timolol
Prostaglandin analogues
Other agents
Tablets  This pharmacology-related article is a stub. You can help Wikipedia by expanding it.

Wikipedia content modification information:

  • This page was last modified on 1 October 2008, at 02:12.

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