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Chlortalidone
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| Systematic (IUPAC) name | |
| 2-chloro-5-(1-hydroxy-3-oxo-1,2-dihydroisoindol-1-yl)- benzenesulfonamide | |
| Identifiers | |
| CAS number | |
| ATC code | C03 |
| PubChem | |
| DrugBank | |
| Chemical data | |
| Formula | C14H11ClN2O4S |
| Mol. mass | 338.767 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Protein binding | 75% |
| Metabolism | ? |
| Half life | 40 hours |
| Excretion | Renal |
| Therapeutic considerations | |
| Pregnancy cat. | |
| Legal status | |
| Routes | Oral |
Chlortalidone (formerly spelled chlorthalidone in the UK, and still so called in the United States) is a drug used to treat hypertension. It is described as a thiazide diuretic (or, rather, a thiazide-like diuretic because it acts similarly to the thiazides but does not contain the benzothiadiazine molecular structure).
It is also available in the UK as a combination product with the beta blocker atenolol as Co-tenidone.
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Wikipedia content modification information:
- This page was last modified on 4 July 2008, at 06:57.
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