This MedLibrary.org supplementary page on Cis-acting is provided directly from the open source Wikipedia as a service to our readers. Please see the note below on authorship of this content, as well as the Wikipedia usage guidelines. To search for other content from our encyclopedia supplement, please use the form below:
Related Sponsors
In the field of molecular biology, cis-acting generally means "acting from the same molecule" (i.e., intramolecular). It may be considered the opposite of trans-acting which generally means "acting from a different molecule" (i.e., intermolecular).
In the context of transcription regulation, cis-acting elements are usually considered to be DNA sequences that, via transcription factors or other trans-acting elements or factors, regulate the expression of genes on the same chromosome.1 The "operator" in the lac operon is an example of a cis-acting regulatory sequence. This DNA sequence is bound by the lac repressor which in turn prevents transcription of the adjacent genes on the same DNA molecule. The lac operator is thus considered to "act in cis" on the regulation of the nearby genes. The operator itself doesn't code for any protein or RNA.
See also
References
- ^ Watson, James D.; Caudy, Amy A, Myers, Richard M., Witkowski, Jan A. (2007). Recombinant DNA: Genes and Genomes - A Short Course, Cold Spring Harbor Press. pp. 57-58. ISBN 0-7167-2866-4.
 |
This biochemistry article is a stub. You can help Wikipedia by expanding it. |
Wikipedia content modification information:
- This page was last modified on 25 June 2008, at 04:37.
Wikipedia Authorship and Review
Wikipedia content provided here is not reviewed directly by MedLibrary.org. Wikipedia content is authored by an open community of volunteers and is not produced by or in any way affiliated with MedLibrary.org.
Wikipedia Usage Guidelines
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article on "Cis-acting".
The URL for this specific entry is:
All Wikipedia text is available under the terms of the GNU Free Documentation License. (See Copyrights for details). Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc.