Clorgiline

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Clorgiline
Systematic (IUPAC) name
N-[3-(2,4-dichlorophenoxy)propyl]-N-methyl-
prop-2-yn-1-amine
Identifiers
CAS number 17780-72-2
ATC code  ?
PubChem 4380
Chemical data
Formula C13H15Cl2NO 
Mol. mass 272.17 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes  ?

Clorgiline (INN) or clorgyline is an inhibitor of monoamine oxidase type A,[1] structurally related to pargyline. It has antidepressant activity, and may potentially be useful in the treatment of Parkinson's disease.

References

  1. ^ Murphy DL, Karoum F, Pickar D, et al (1998). "Differential trace amine alterations in individuals receiving acetylenic inhibitors of MAO-A (clorgyline) or MAO-B (selegiline and pargyline)". J. Neural Transm. Suppl. 52: 39–48. PMID 9564606. 

Wikipedia content modification information:

  • This page was last modified on 3 October 2008, at 17:15.

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