This MedLibrary.org supplementary page on Co-codamol is provided directly from the open source Wikipedia as a service to our readers. Please see the note below on authorship of this content, as well as the Wikipedia usage guidelines. To search for other content from our encyclopedia supplement, please use the form below:
Related Sponsors
|
Co-codamol
|
|
| Combination of | |
| Codeine | Opiate analgesic |
| Paracetamol | Non-opioid analgesic |
| Identifiers | |
| CAS number | ? |
| ATC code | N02 |
| PubChem | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
C(US) |
| Legal status | |
| Routes | Oral |
Co-codamol (BAN) is a non-proprietary name used to denote a compound analgesic, a combination of codeine phosphate and paracetamol (acetaminophen). Co-codamol tablets are used for the relief of mild/moderate (or in the case of 30/500mg - severe) pain.
Contents |
Formulations
Four strengths are available:
- 8mg of codeine phosphate per tablet
- 12.8mg of codeine phosphate per tablet
- 15mg of codeine phosphate per tablet*
- 30mg of codeine phosphate per tablet (available in capsules as Tylex, available in tablets/caplets as Solpadol, Kapake and Zapain).
Formulations contain from 300 mg to 1000 mg of paracetamol per tablet[1]. In the United Kingdom the 15/500 and 30/500 tablets are available only with a prescription, and the 8/500 12.8/500 strength is available over the counter. This is also the case in Australia, however 15/500 tablets in packs of 12 or less are Schedule 3 (Pharmacist Only Medicine). Manufacturer directions state not to exceed more than the recommended dosage of two tablets every four hours, and no more than eight in a 24 hour period. Do not take more than 2 at any one time. Other drugs containing paracetamol should be avoided.
In the United States, Tylenol produces tablets containing 8, 15, and 30 milligrams, named Tylenol No.1, 2, and 3, respectively. There is also a Tylenol 4 containing 60mg of codeine. All tablets contain 300mg of paracetamol. No Tylenol with codeine products in the U.S. contain caffeine. In Canadian preparations Tylenol #2 & #3 contain 15mg caffeine.
Co-codamol is marketed in the United States and Canada as Tylenol 3 with Codeine, in the UK as both Solpadeine and Solpadol and in Australia as Panadeine, Panadeine 15 and Panadeine Forte.
Side effects
Side effects can include: constipation, skin rashes, dizziness, sedation, shortness of breath, hypersensitivity reaction, fainting (syncope or near syncope), nausea and/or vomiting, confusion, loss of short-term memory, drowsiness, changes in blood, allergic reactions, euphoria, dysphoria, abdominal pain, pruritus (itching), easy bruising and bleeding gums.
Genetic differences between people gives rise to differing rates of metabolism of codeine to morphine. In about 5% of people this may happen particularly fast, leading to higher levels of morphine being passed through breast milk in amounts potentially able to cause fatal respiratory depression of a breastfed baby.[2]
References
- ^ Tylenol with Codeine, from Drugs.com
- ^ CTV News, Codeine use while breastfeeding may be dangerous, Wed. Aug. 20 2008 9:42 PM ET
See also
 |
This psychoactive drug-related article is a stub. You can help Wikipedia by expanding it. |
|
|||||||||||||||||||||||||||||||||||||||||||||
Wikipedia content modification information:
- This page was last modified on 19 September 2008, at 18:56.
Wikipedia Authorship and Review
Wikipedia content provided here is not reviewed directly by MedLibrary.org. Wikipedia content is authored by an open community of volunteers and is not produced by or in any way affiliated with MedLibrary.org.
Wikipedia Usage Guidelines
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article on "Co-codamol".
The URL for this specific entry is:
All Wikipedia text is available under the terms of the GNU Free Documentation License. (See Copyrights for details). Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc.