Colesevelam

This MedLibrary.org supplementary page on Colesevelam is provided directly from the open source Wikipedia as a service to our readers. Please see the note below on authorship of this content, as well as the Wikipedia usage guidelines. To search for other content from our encyclopedia supplement, please use the form below:

Related Sponsors

BM Pharmacy Generic pharmaceuticals at unbeatable prices. Insomnia, men's health, hair health, pain control. bmpharmacy.com
Online Pharmacy Carisoprodol, tadalafil, sildenafil, vardenafil and more... xlpharmacy.com
MedBasket.com Discreet. Inexpensive. Fast shipping. Great selection. What more can we say? medbasket.com
Frugalmed 2000 reasons to shop with us first. frugalmed.com
Ads by Tiva

Colesevelam
Systematic (IUPAC) name
2-(chloromethyl)oxirane; prop-2-en-1-amine; N-prop-2-enyldecan-1-amine; trimethyl-[6-(prop-2-enylamino)hexyl]azanium; chloride; hydrochloride
Identifiers
CAS number 182815-44-7
ATC code C10AC04
PubChem 160051
Chemical data
Formula Cl3H67N4O 
Mol. mass 618.248 g/mol
Pharmacokinetic data
Bioavailability n/a
Metabolism Not metabolized by the body, Colesevelam is not absorbed by the body.
Half life n/a (non-systemic drug)
Excretion By intestines only, Colesevelam is 100% non-systemic
Therapeutic considerations
Pregnancy cat.

B
Legal status

℞ Prescription only
Routes Oral

Colesevelam is a bile acid sequestrant administered orally. It is developed by Genzyme and marketed in the US by Daiichi Sankyo under the brand name WelChol and elsewhere by Genzyme under the tradename Cholestagel.

Clinical use

Colesevelam is indicated as an adjunct to diet and exercise to reduce elevated low-density lipoprotein cholesterol (LDL-C) in patients with primary hyperlipidemia as monotherapy or in combination with an hydroxymethyl-glutaryl-coenzyme A (HMG CoA) reductase inhibitor and to improve glycemic control in adults with type 2 diabetes mellitus.

External links

v • d • e
Lipid modifying agents (C10)
Statins
Fibrates
Bile acid sequestrants
Colestyramine • Colestipol • Colestilan • Colextran • Colesevelam
Niacin and derivatives
CETP inhibitors
Combinations
Other
†Undergoing clinical trials. ‡Withdrawn from market. §Development terminated.

Wikipedia content modification information:

  • This page was last modified on 27 May 2008, at 17:54.

Wikipedia Authorship and Review

Wikipedia content provided here is not reviewed directly by MedLibrary.org. Wikipedia content is authored by an open community of volunteers and is not produced by or in any way affiliated with MedLibrary.org.

Wikipedia Usage Guidelines

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article on "Colesevelam".

The URL for this specific entry is:

All Wikipedia text is available under the terms of the GNU Free Documentation License. (See Copyrights for details). Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc.