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Corticorelin
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| Systematic (IUPAC) name | |
| ? | |
| Identifiers | |
| CAS number | |
| ATC code | V04 |
| PubChem | |
| Chemical data | |
| Formula | C205H339N59O63S |
| Mol. mass | 4670.31 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
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| Legal status | |
| Routes | ? |
Corticorelin is a diagnostic agent. The corticorelin stimulation test helps to differentiate between the etiologies of ACTH-dependent hypercortisolism. It is used to evaluate the status of the pituitary-adrenal axis in the differentiation of a pituitary source from an ectopic source of excessive ACTH secretion. If corticorelin injection increases plasma levels of ACTH and cortisol, a diagnosis of Cushing's Disease is acheived (ACTH of pituitary origin). If corticorelin injection leads to little or no response in plasma levels of ACTH or cortisol, a diagnosis of Ectopic ACTH Syndrome is confirmed.
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Wikipedia content modification information:
- This page was last modified on 16 November 2008, at 20:09.
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