Cytidine monophosphate

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Cytidine monophosphate
Chemical name 5'-Cytidylic acid
Chemical formula C9H14N3O8P
Molecular mass 323.20 g/mol
CAS number 63-37-6
SMILES O[C@H]1[C@H]([C@H]
(N2C=CC(N)=NC2=O)O
[C@@H]1COP(O)(O)=O)O
Chemical structure of deprotonated CMP

Cytidine monophosphate, also known as 5'-cytidylic acid or simply cytidylate, and abbreviated CMP, is a nucleotide that is found in RNA. It is an ester of phosphoric acid with the nucleoside cytidine. CMP consists of the phosphate group, the pentose sugar ribose, and the nucleobase cytosine.

Metabolism

CMP can be phosphorylated to cytidine diphosphate by the enzyme CMP kinase, with adenosine triphosphate or guanine triphosphate donating the phosphate group. Since cytidine triphosphate is generated by amination of uridine triphosphate, the main source of CMP is from RNA being decomposed, eg. by RNAse.

See also


External links

v • d • e
Nucleobases, nucleosides, and nucleotides
Nucleobases
Nucleosides/
(NB+pentose)
Nucleotides/
(NS+phosphate)
monophosphates (AMP, GMP, UMP, CMP) | diphosphates (ADP, GDP, UDP, CDP) | triphosphates (ATP, GTP, UTP, CTP)
monophosphates (dAMP, dGMP, dUMP, TMP, dCMP) | diphosphates (dADP, dGDP, TDP, dCDP) | triphosphates (dATP, dGTP, TTP, dCTP)
Major families of biochemicals
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Alkaloids | Nucleobases | Nucleic acids | | Enzyme cofactors | Flavonoids | Polyketides | Tetrapyrroles
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