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Danaparoid
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| ATC code | B01 |
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Danaparoid sodium (Orgaran) is an anticoagulant that works by inhibiting activated factor X (factor Xa).
Danaparoid is considered a "low molecular weight heparin" by some sources, but is chemically distinct from heparin and thus has little cross-reactivity in heparin-intolerant patients.
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Uses
It is used to prevent deep venous clots, particularly in situations with a high risk of clot formation, such as after hip surgery.
It is also used as a heparinoid substitute in heparin-induced thrombocytopenia which may otherwise cause paradoxical thrombosis.
Discontinuation
On August 14, 2002, this drug was withdrawn by Organon International.[1]
Administration
IV IV and SC
Side effects
- Bleeding problems
- Low platelets, due to a low level of structural similarity between danaparoid and heparin
- Asthma exacerbations, due to allergies to sulfites contained within the medicine
References
- ^ "Danaparoid (Subcutaneous Route) - MayoClinic.com". Retrieved on 2007-08-23.
External links
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Wikipedia content modification information:
- This page was last modified on 18 July 2008, at 13:00.
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