This MedLibrary.org supplementary page on Delorazepam is provided directly from the open source Wikipedia as a service to our readers. Please see the note below on authorship of this content, as well as the Wikipedia usage guidelines. To search for other content from our encyclopedia supplement, please use the form below:
Related Sponsors
 |
|
 |
|
|
Delorazepam
|
|
| Systematic (IUPAC) name | |
| (7-Chloro-5-(o-chlorophenyl) -1,3-dihydro-2H-1,4-benzodiazepin-2-one) | |
| Identifiers | |
| CAS number | ? |
| ATC code | ? |
| PubChem | |
| DrugBank | |
| Chemical data | |
| Formula | C15H10Cl2N2O |
| Mol. mass | 304.02 |
| Pharmacokinetic data | |
| Bioavailability | 87% |
| Metabolism | Hepatic |
| Half life | [60-140] |
| Excretion | Renal |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status |
? |
| Routes | Oral |
Delorazepam also known as chlordesmethyldiazepam is a drug which is a benzodiazepine derivative. It's mainly used in Italy, where it is available under the trade name "En".
The potency of delorazepam is very high, and probably 1 mg delorazepam equals 10 mg diazepam.
In adult half life is 99.7 (±22.3) hours for cpr and 96.9 (±19.7) hours for drops after a single dose of 1 mg. In children half life is about 40 hours for children of 7 months, 27 hours for children between 2 and 3 years, 34 hours for more than 3 years.
Total clearance after single administration of 2 mg is 0.11 ml/min/kg.
 |
This pharmacology-related article is a stub. You can help Wikipedia by expanding it. |
|
|||||||||||||||||||||||||||||
Wikipedia content modification information:
- This page was last modified on 7 August 2008, at 22:46.
Wikipedia Authorship and Review
Wikipedia content provided here is not reviewed directly by MedLibrary.org. Wikipedia content is authored by an open community of volunteers and is not produced by or in any way affiliated with MedLibrary.org.
Wikipedia Usage Guidelines
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article on "Delorazepam".
The URL for this specific entry is:
All Wikipedia text is available under the terms of the GNU Free Documentation License. (See Copyrights for details). Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc.