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Dimethylthiambutene
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| Systematic (IUPAC) name | |
| N,N-dimethyl-4,4-dithiophen-2-yl-but-3-en-2-amine | |
| Identifiers | |
| CAS number | |
| ATC code | ? |
| PubChem | |
| Chemical data | |
| Formula | C14H17NS2 |
| Mol. mass | 263.424 g/mol |
| SMILES | & |
| Physical data | |
| Melt. point | 169–170 °C (336–338 °F) |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | ? |
Dimethylthiambutene (N,N-Dimethyl-1-methyl-3,3-di-2-thienylallylamine, Ohton, Aminobutene, Dimethibutin, Kobaton, Takaton, Dimethibutin) is an opioid analgesic drug, most often used in veterinary medicine in Japan and to a lesser extent in other countries in the region and around the world. It is the most prominent and widely-used of the thiambutenes, a series of open-chain opioids structurally related to methadone which are also called the thienyl derivative opioids which also includes diethylthiambutene and ethylmethylthiambutene as well as the cough suppressant tipepidine, which is weaker and not a controlled substance in most of the world.
Dimethylthiambutene was developed in the United States in the early 1950s and introduced to the market by Burroughs-Wellcome in the United Kingdom in 1951. Dimethylthiambutene is now under international control under the UN Single Convention on Narcotic Drugs 1961, the laws governing habit-forming substances in virtually all countries and Schedule I of the US Controlled Substances Act of 1970 due to high abuse potential and never being introduced clinically in the United States; other countries regulate it much as morphine or heroin.
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- This page was last modified on 20 June 2008, at 03:36.
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