Dimethyltubocurarine

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Dimethyltubocurarinium
Systematic (IUPAC) name
 ?
Identifiers
CAS number  ?
ATC code M03AA04
PubChem 21233
DrugBank APRD01318
Chemical data
Formula C40H48N2O6+2
Mol. mass 652.819 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?
Legal status
Routes  ?

Dimethyltubocurarinium (INN) or metocurine (USAN), also known as dimethyltubocurarine, is a non-depolarizing muscle relaxant.

Tablets  This pharmacology-related article is a stub. You can help Wikipedia by expanding it.
v • d • e
Skeletal Muscle relaxants (M03)
Peripherally acting
(primarily antinicotinic,
NMJ blocking)
Curare alkaloids
Alcuronium · Dimethyltubocurarine · Tubocurarine
short duration: Mivacurium

intermediate: Atracurium/Cisatracurium · Fazadinium · Rocuronium (short onset) · Vecuronium

long: Doxacurium · Metocurine · Pancuronium · Pipecuronium

unsorted: Gallamine · Hexafluronium
Centrally acting
Other
Directly acting
v • d • e
Anticholinergics
Nicotinic antagonists
nondepolarizing (Mecamylamine, Trimetaphan, Hexamethonium) · Nicotine (high doses)
note: in PNS, ganglionic blocker can have direct antinicotinic action at preganglionic terminal, but simulate indirect antimuscarinic activities at postganglionic terminal
Curare alkaloids
Alcuronium · Dimethyltubocurarine · Tubocurarine
short duration: Mivacurium

intermediate: Atracurium/Cisatracurium · Fazadinium · Rocuronium (short onset) · Vecuronium

long: Doxacurium · Metocurine · Pancuronium · Pipecuronium

unsorted: Gallamine · Hexafluronium
Muscarinic antagonists
nonpolar/tertiary/CNS: Atropine · Scopolamine · Hyoscyamine · antiparkinson drugs (Benzatropine, Trihexyphenidyl, Biperiden)

polar/quarternary/non-CNS: Glycopyrrolate · Ipratropium · M1 (Pirenzepine) · M3 (Tiotropium, Darifenacin, Vedaclidine)

unsorted: Tropicamide · Cyclopentolate · Dicycloverine · Tolterodine · Oxybutynin · Homatropine  · Orphenadrine · Diphenhydramine · Other ethanolamine class first-generation antihistamines
Indirect
acetylcholine synthesis inhibitor (Hemicholinium-3) · vesicle storage inhibitor (Vesamicol) · acetylcholine release inhibitor (Botulinum toxin) · acetylcholine release stimulator (Alpha-latrotoxin) · acetylcholinesterase reactivators (Pralidoxime, Obidoxime)
 This chemistry article is a stub. You can help Wikipedia by expanding it.

Wikipedia content modification information:

  • This page was last modified on 11 October 2008, at 03:26.

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