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Drug delivery is the method or process of administering a pharmaceutical compound to achieve a therapeutic effect in humans or animals[1] [2]. Drug Delivery technologies are patent protected formulation technologies that modifies drug release profile, absorption, distribution and elimination for the benefit of improving product efficacy & safety and patient convenience & compliance[3]. Most common methods of delivery include the preferred non-invasive peroral (through the mouth), topical (skin), transmucosal (nasal, buccal/sublingual, vaginal, ocular and rectal) and inhalation routes [4][5]. Many medications such as peptide and protein, antibody, vaccine and gene based drugs, in general may not be delivered using these routes because they might be susceptible to enzymatic degradation or can not be absorbed into the systemic circulation efficiently due to molecular size and charge issues to be therapeutically effective. For this reason many protein and peptide drugs have to be delivered by injection. For example, many immunizations are based on the delivery of protein drugs and are often done by injection.
Current efforts in the area of drug delivery include the development of targeted delivery in which the drug is only active in the target area of the body (for example, in cancerous tissues) and sustained release formulations in which the drug is released over a period of time in a controlled manner from a formulation.
See also
References
- M. N. V. Ravi Kumar (2008), Handbook of Particulate Drug Delivery (2-Volume Set), American Scientific Publishers. ISBN 1-58883-123-X
- ^ "Definition". Retrieved on 2008-05-01.
- ^ "Definition". Retrieved on 2008-05-01.
- ^ "Definition". Retrieved on 2008-05-26.
- ^ "Definition". Retrieved on 2008-05-27.
- ^ "Definition". Retrieved on 2008-05-27.
External links
- Drug Delivery Technology
- The 9th US-Japan Symposium on Drug Delivery Systems
- Article in Chemical and Engineering News
- Drug Delivery News and Analysis
- Drug Delivery Reports
- Nanotechnology in Drug Delivery
- Drug Delivery Market
- Future of Drug Delivery Industry
- Drug Delivery Unmet Needs
Wikipedia content modification information:
- This page was last modified on 4 October 2008, at 15:45.
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