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| Dyslipidemia Classification and external resources |
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| ICD-10 | E78. | |
|---|---|---|
| ICD-9 | 272 | |
| MeSH | C18.452.339 | |
Dyslipidemia is a disruption in the amount of lipids in the blood.
In western societies, most dyslipidemias are hyperlipidemias; that is, an elevation of lipids in the blood, often due to diet and lifestyle. The prolonged elevation of insulin levels can lead to dyslipidemia. Increased levels of O-GlcNAc transferase (OGT) are known to cause dylipidaemia.[1]
Contents |
Classification
There are two major ways in which dyslipidemias are classified:
- Phenotype, or the presentation in the body (including the specific type of lipid that is increased)
- Etiology, or the reason for the condition (genetic, or secondary to another condition.) This classification can be problematic, because most conditions involve the intersection of genetics and lifestyle issues. However, there are a few well defined genetic conditions that are usually easy to identify.
Types
Increases
- These conditions are discussed in greater detail at hyperlipidemia.
- Hyperlipidemia: lipids
- Hypercholesterolemia: cholesterol
- Hyperglyceridemia: glycerides
- Hypertriglyceridemia: triglycerides
- Hyperlipoproteinemia: lipoproteins (usually LDL unless otherwise specified)
- Hyperchylomicronemia: chylomicrons
- Combined hyperlipidemia: both LDL and triglycerides
Familial hypercholesterolemia is a specific form of hypercholesterolemia due to a defect on chromosome 19 (19p13.1-13.3).
Decreases
- Hypolipoproteinemia: lipoproteins
- Hypocholesterolemia: cholesterol
- Abetalipoproteinemia: beta lipoproteins
- Tangier disease: high density lipoprotein
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Wikipedia content modification information:
- This page was last modified on 12 June 2008, at 18:14.
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