Enprostil

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Enprostil
Systematic (IUPAC) name
Methyl 7-[(1R,2R,3R)- 3-hydroxy-2-[(1E,3R)- 3-hydroxy-4-phenoxy-1-butenyl]-5-oxocyclopentyl]- 4,5-heptadienoate
Identifiers
CAS number 73121-56-9
ATC code A02BB02
PubChem 51744
Chemical data
Formula C23H28O6 
Mol. mass 400.46 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?
Legal status
Routes  ?

Enprostil is a synthetic prostaglandin designed to resemble dinoprostone.

It is classified by the World Health Organization under "A02B: Drugs for peptic ulcer and gastro-oesophageal reflux disease."

External links

  • Toshina K, Hirata I, Maemura K, Sasaki S, Murano M, Nitta M, Yamauchi H, Nishikawa T, Hamamoto N, Katsu K (2000). "Enprostil, a prostaglandin-E(2) analogue, inhibits interleukin-8 production of human colonic epithelial cell lines.". Scand J Immunol 52 (6): 570–5. doi:10.1046/j.1365-3083.2000.00815.x. PMID 11119262. 
  • Tari A, Hamada M, Kamiyasu T, Sumii K, Haruma K, Inoue M, Kishimoto S, Kajiyama G, Walsh J (1997). "Effect of enprostil on omeprazole-induced hypergastrinemia and inhibition of gastric acid secretion in peptic ulcer patients.". Dig Dis Sci 42 (8): 1741–6. doi:10.1023/A:1018825902055. PMID 9286243. 
  • Ching C, Lam S (1995). "A comparison of two prostaglandin analogues (enprostil vs misoprostol) in the treatment of acute duodenal ulcer disease.". J Gastroenterol 30 (5): 607–14. doi:10.1007/BF02367786. PMID 8574332. 


 This biochemistry article is a stub. You can help Wikipedia by expanding it.
Tablets  This pharmacology-related article is a stub. You can help Wikipedia by expanding it.
v • d • e
Drugs for acid related disorders: Drugs for peptic ulcer and GERD/GORD (A02B)
H2 antagonists
Prostaglandins/analogues
Misoprostol, Enprostil
Proton pump inhibitors
Other
v • d • e
Eicosanoids: prostaglandins
Endogenous/series 2
Prostaglandin analogues

Wikipedia content modification information:

  • This page was last modified on 31 May 2008, at 13:43.

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