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Etofibrate
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| Systematic (IUPAC) name | |
| 2-{[2-(4-chlorophenoxy)-2-methylpropanoyl]oxy}ethyl nicotinate | |
| Identifiers | |
| CAS number | |
| ATC code | C10 |
| PubChem | |
| Chemical data | |
| Formula | C18H18ClNO5 |
| Mol. mass | 363.792 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | Hydrolyzed to clofibric acid and niacin |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | ? |
Etofibrate is a fibrate. It is a combination of clofibrate and niacin, linked together by an ester bond. In the body, clofibrate and niacin separate and are released gradually, in a manner similar to controlled-release formulations.[1]
References
- ^ Sposito AC, Mansur AP, Maranhão RC, Rodrigues-Sobrinho CR, Coelho OR, Ramires JA (2001). "Etofibrate but not controlled-release niacin decreases LDL cholesterol and lipoprotein (a) in type IIb dyslipidemic subjects". Braz J Med Biol Res 34 (2): 177–82. PMID 11175492. Free full text
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Wikipedia content modification information:
- This page was last modified on 15 August 2007, at 16:02.
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