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| Factor XIII deficiency Classification and external resources |
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| ICD-10 | D68.2 |
|---|---|
| ICD-9 | 286.3 |
| OMIM | 134570 134580 |
| DiseasesDB | 31412 |
| eMedicine | ped/3040 |
| MeSH | D005177 |
Factor XIII deficiency may occur very rarely, and can cause a severe bleeding tendency. Incidence is 1 in a million to 1 in 5 million people. Most are due to mutations in the A subunit. Administration of recombinant A subunit improves clot stability and may become a therapeutic option for patients with this condition[1].
See also
References
- ^ Lovejoy A, Reynolds T, Visich J, Butine M, Young G, Belvedere M, Blain R, Pederson S, Ishak L, Nugent D (2006). "Safety and pharmacokinetics of recombinant factor XIII-A2 administration in patients with congenital factor XIII deficiency.". Blood 108 (1): 57–62. doi:. PMID 16556896.
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- This page was last modified on 8 July 2008, at 17:28.
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