Fletazepam

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Fletazepam
Systematic (IUPAC) name
7-chloro-5-(2-fluorophenyl)-1-(2,2,2-trifluoroethyl)-2,3-dihydro-1,4-benzodiazepine
Identifiers
CAS number 34482-99-0
ATC code  ?
PubChem 36834
Chemical data
Formula C17H13ClF4N2 
Mol. mass 356.745
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status
Routes  ?

Fletazepam is a drug which is a benzodiazepine derivative. It has sedative and anxiolytic effects similar to those produced by other benzodiazepine derivatives, but is mainly notable for its strong muscle relaxant properties.[1]

Fletazepam is most closely related to other N-trifluoroethyl substituted benzodiazepines such as halazepam and quazepam.[2]



References

  1. ^ Barnett A, Goldstein J, Fiedler EP, Taber RI. The pharmacology of fletazepam, a centrally-acting muscle relaxant. Archives Internationales de Pharmacodynamie et de Therapie. 1974 Nov;212(1):164-74.
  2. ^ Orio LC, Barnett A, Billard W. Selective affinity of 1-N-trifluoroethyl benzodiazepines for cerebellar type 1 receptor sites. Life Sciences, 1984. (35):105-113.

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  • This page was last modified on 23 September 2007, at 04:36.

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