Fluvastatin

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Fluvastatin
Systematic (IUPAC) name
7-[3-(4-fluorophenyl) -1-(1-methylethyl) -1H-indol-2-yl]-3, 5-dihydroxy-hept-6-enoic acid
Identifiers
CAS number 93957-54-1
ATC code C10AA04
PubChem 1548972
DrugBank APRD00346
Chemical data
Formula C24H26FNO4 
Mol. mass 411.466 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding 98%
Metabolism  ?
Half life 2.5 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?
Legal status
Routes  ?

Fluvastatin (Lescol, Canef) is a member of the drug class of statins, used to treat hypercholesterolemia and to prevent cardiovascular disease. It has also been shown to exhibit antiviral activity against Hepatitis C.[1]

References

  1. ^ Bader T, Fazili J, Madhoun M, et al (April 2008). "Fluvastatin Inhibits Hepatitis C Replication in Humans". Am. J. Gastroenterol. 103: 1383. doi:10.1111/j.1572-0241.2008.01876.x. PMID 18410471. 
v • d • e
Lipid modifying agents (C10)
Statins
Fibrates
Bile acid sequestrants
Niacin and derivatives
CETP inhibitors
Combinations
Other
†Undergoing clinical trials. ‡Withdrawn from market. §Development terminated.
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Wikipedia content modification information:

  • This page was last modified on 21 June 2008, at 14:53.

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